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BIOL 315 Quiz 7
Terms in this set (22)
T/F Mammals have a direct mechanism for thymine-thymine dimerization repair that involves the activity of photolyase. Photolyase is activated by blue light.
T/F The nucleotide excision repair (NER) mechanism includes two proteins to cut a section of the DNA that includes the lesion. These proteins are UvrA and UvrB.
UvrB and UvrC
T/F The Uvr proteins of E. coli are only responsible for repairing mutations caused by UV light exposure.
T/F In methyl-directed mismatch repair, the MutS protein functions to recognize and bind a mismatch in the DNA helix to initiate the repair mechanism.
T/F MutL, also part of the methyl-directed mismatch repair, functions to nick the unmethylated strand as part of the repair process.
T/F Clastogen is a protein essential for repairing double stranded chromosome breaks.
T/F Nonspecific trimming of DNA at double stranded break sites always occurs during postreplicative gap repair.
T/F RecA binds to ssDNA as part of the non homologous end joining mechanism to repair double stranded chromosome breaks.
T/F The SOS response in bacteria does not involve a recombination-like repair mechanism.
T/F The SOS response in bacteria allows the cell to pause and repair DNA before undergoing the next cell division.
T/F If a primary nondisjunction event happens, then half the resulting gametes will have normal numbers of chromosomes.
all four gametes are abnormal;
2 are (n + 1) and 2 are (n - 1)
T/F A Robertsonian translocation results in a familial form of Downs syndrome.
T/F An allotetraploid contains two chromosome sets each from two closely related species.
T/F Members of the same species can have copy number differences for the same gene, caused by non allelic homologous recombination, transposable elements, or DNA replication errors.
T/F Position effect is a term that refers to the fact that as long as a gene has its own promoter, it will be expressed correctly even if the genomic location for the gene changes.
location of the gene affects the correct function of the promoter
T/F Seedless watermelon plants are considered to be triploid.
T/F Familial down syndrome is due to a translocation event between chromosome 14 and 21.
T/F Aneuploidy is commonly the loss or gain of a single chromosome in a normal set.
loss or gain of 1 or more chromosomes, but not a complete set
T/F An intragenic suppressor mutation is a second mutation in the same gene as a first mutation. This suppressor mutation restores phenotype to wild type.
restores phenotype without correcting mutated genotype
T/F A chromosome inversion may not cause the loss of genetic material, but it can affect meiotic synapsis in an individual heterozygous for the inversion.
T/F During meiotic synapsis, an individual heterozygous for a chromosomal deletion will have a compensation loop form on the mutant allele so it can pair up optimally with the wild-type allele.
compensation loop/deletion loop forms on the WT allele
T/F A phenomenon called gene amplification is thought to be due to over expression of genes near inverted sequences.
genes near duplicated sequences
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