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Science
Biology
Immunology
Chapter 35 Assessment of Immune Function -Brunner & Suddarth
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Terms in this set (55)
antibody
a (large) protein substance developed by the body in response to and interacting with a specific antigen
aka immunoglobulins, consist of two sub-units, each containing a light and a heavy peptide chain held together by a chemical link made up of disulfide bonds
antigen
substance that induces the production of antibodies
apoptosis
programmed cell death that results from the digestion of deoxyribonucleic acid by end nucleases
B cells
cells that are important for producing a humoral immune response
make up about 10% to 15% of lymphocytes in the blood
cellular immune response
the immune system's third line of defense, involving the attack of pathogens by T cells
complement
series of enzymatic proteins in the serum that, when activated, destroy bacteria and other cells
cytokines
generic term for nonantibody proteins that act as intercellular mediators, as in the generation of immune response. When activated by T-cells they attract and activate B cells, cytotoxic T cells, NK cells, macrophages, and other cells of the immune system
cytotoxic T cells
(killer T-cells)
lymphocytes that lyse cells infected with virus; also play a role in graft rejection
-attack the antigen directly by altering the cell membrane, causing cell lysis
helper T cells
lymphocytes that attack foreign invaders (antigens) directly
-secrete cytokines, which attract and activate B cells, cytotoxic T cells, NK cells, and macophages, and other immune cells
-contribute to the differentiation of null & NK cells
humoral immune response
the immune system's second line of defense; often termed the antibody response
immune response
the coordinated response of the components of the immune system to a foreign agent or organism
immune system
the collection of organs, cells, tissues, and molecules that mediate the immune response
immunity
the body's specific protective response to a foreign agent or organism; resistance to disease, specifically infectious diseases
immunoregulation
complex system of checks and balances that regulates or controls immune responses
memory cells
cells that are responsible for recognizing antigens from previous exposure and mounting an immune response
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Verified questions
BIOLOGY
Which organelle converts the chemical energy in food into a form that cells can use? a. nucleolus b. chromosome c. mitochondrion d. chloroplast
BIOLOGY
What is probabulity?
BIOLOGY
Human genomic DNA was digested with the various restriction enzymes noted in the list below. These digests were subjected to electrophoresis on an agarose gel; the DNA separated in the gel was then stained with ethidium bromide, and a photograph of the fluorescence was taken. The DNA in the gel was transferred to a nitrocellulose filter to make a Southern blot, and this blot was then probed with a radioactive 5 kb-long fragment of cloned human DNA with EcoRI sites at both ends. The sizes of the dark bands seen on an X-ray film exposed to the Southern blot for each digest were EcoRI: 5 kb; KpnI: 2.5 kb, 6 kb; HindIII: 8 kb; EcoRI + KpnI: 4 kb, 1 kb; EcoRI + HindIII: 5 kb; KpnI: + HindIII: 2.5 kb, 4.5 kb. a. Why were these digests separated by electrophoresis on agarose gels rather than polyacrylamide gels? b. Describe what you would see on the photograph of the ethidium bromide-stained gel. c. In this problem, the sums of the sizes of all the dark bands seen on the X-ray film of the Southern blot are not the same for all the digests reported. However, in previous problems involving restriction mapping, all the digests of a particular DNA sample produce fragments the sum of whose sizes are the same. Explain this difference. d. Draw a restriction map that accounts for the results of this Southern blot. e. Can you orient the restriction map you drew in part d to the centromere-to-telomere direction along the human chromosome on which these DNA sequences are located?
BIOLOGY
You learn that a dandelion is in the same kingdom as pine trees. Name three characteristics that these organisms share.
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