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Terms in this set (89)

anticholinergics, antimuscarinics

Inhibits the action of acetylcholine at postganglionic sites located in: Smooth muscle,Secretory glands, CNS (antimuscarinic activity). Low doses decrease: Sweating, Sali-vation, Respiratory secretions. Intermediate doses result in: Mydriasis (pupillary di-lation), Cycloplegia (loss of visual accommodation), Increased heart rate. GI and GUtract motility are decreased at larger doses.TherapeuticEffects:Increased heartrate. Decreased GI and respiratory secretions. Reversal of muscarinic effects. Mayhave a spasmolytic action on the biliary and genitourinary tract

Adverse Reactions/Side Effects
CNS:drowsiness, confusion, hyperpyrexia.EENT:blurred vision, cycloplegia, pho-tophobia, dry eyes, mydriasis.CV:tachycardia, palpitations, arrhythmias.GI:drymouth, constipation, impaired GI motility.GU:urinary hesitancy, retention, impo-tency.Resp:tachypnea, pulmonary edema.Misc:flushing, decreased sweating.

Patient/Family Teaching
●May cause drowsiness. Caution patients to avoid driving or other activities requir-ing alertness until response to medication is known.
●Instruct patient that oral rinses, sugarless gum or candy, and frequent oral hygienemay help relieve dry mouth.
●Caution patients that atropine impairs heat regulation. Strenuous activity in a hotenvironment may cause heat stroke.Advise patient to notify health care profes-sional of all Rx or OTC medications, vitamins, or herbal products being taken andto consult with health care professional before taking other medications.
●Pedi:Instruct parents or caregivers that medication may cause fever and to notifyhealth care professional before administering to a febrile child.
●Geri:Inform male patients with benign prostatic hyperplasia that atropine maycause urinary hesitancy and retention. Changes in urinary stream should be re-ported to health care professional

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