Archaic humans having sex with less archaic humans (references)
Terms in this set (31)
replacement model: modern humans evolved in africa, left, and replaced everyone/thing else
Wolpoff et al. 2001
multiregional model: a single worldwide species of humans (archaic forms included) met, migrated, had babies together and that's how modern humans were created
Old school model: regional continuity model - humans evolved everywhere at the same time from different regions
Prugnole et al. 2005
African pops are the most genetically diverse, and genetic diversity decreaeses as a function of geogrpahi distance from E/S Africa
Rito et al. 2013
All mitochondrial haplogroups outside of Africa either M or N, variants of those found in Africa...
Briggs et al. 2009
Earlier analysis of neanderthal mtDNA (5 sites) - variation outside of that of humans... probably no admixture
Hellenthal et al. 2014
In general... pretty much all populations show evidence of extensive complex admixture (85% of them)
Harding & McVean 2004
We should be thinking about complex meta-populations in the origins of modern humans... migrating out of africa (mostly) with complex admixture events
Pickrell & Reich 2014
Ancient DNA is changing EVERYTHINGGGG
Prufer et al. 2014
neanderthals and humans... diverged 550000-765000ya (according to genomes) and denisovans and neanderthals... more like 381000-473000ya
Green et al. 2010
Draft sequence neanderthal genome in Croatia... 1-4% of Eurasian genome traced to neanderthal ancestry
Sankararaman et al. 2014
Neanderthal-human gene flow... 47,000-65,000 years ago?
Prufer et al. 2014
Complete neanderthal genome... ancestry slightly higher in East Asian populations (1-5% vs 1-4%)
Meyer et al. 2012
Denisovan genome... shared 4-6% with Oceanian populations ...
Vernot & Akey 2015
Difference european vs east asian neanderthal ancestry... due to an additional pulse of admixture... not less efficient purifying selection
Slon et al. 2018
awww a neanderthal mommmy and a denisovan daddy had a little deneanderthal baby
Kulwilm et al. 2016
Hold up! Altai neanderthal genome has more derived alleles with present-day Africans than either european neanderthals or denisovans.... an earlier introgression from humans some 100,000 years ago.... perhaps in the far east...
Hominin metapopulation model...
A little roundup: most genetic variation result of african ancestry and founder effects and serial bottlenecks as they spread across the globe ... but also admixture
Racimo et al. 2014
archaic haplotypes with functional consequences identified and vary across populations
Vernot & Akey 2014
Perhaps 20% of the neanderthal genome still exists distributed across modern human populations
Sankararaman et al. 2016
a model.... 257 modern genomes, 120 pops, and compared to denisovan and neanderthal genomes... archaic ancestry deserts: especially X chromosomes...
also a bunch of genes seem to have been selected... pigementation... also susceptibility to diabetes, lupus, crohn's, smoking addiction... cool...
Vernot & Akey 2015
different model... find areas that arent in African genomes: same genes found as Sankararararaman and colleagues... male hybrid infertility?
Juric et al. 2016
Quantify strength of selection against neanderthal introgressed regions: suggests weak purifying selection - weakly deleterious genes selected after entering larger effective population sizes
Fu et al. 2016
Consider neanderthal ancestry in ancient genomes of modern humans... indicates a stready decrease in neanderthal ancestry over past 40,000 years .... https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4537386/
Biological species concept: interbreeding
Other species concepts (ecological, phylogenetic, morphological)...
Boyd & Silk 2010
Reference for using when you're bullshitting about features of neanderthals
Hoffecker & Hoffecker 2017
Human dispersal related to technological complexity
DeMonocal & Stringer 2016
Human dispersal related to climate changes
Cann et al. 1987
mtDNA phylogenetic trees point to orogin of ALL modern humans to female ancestor in Africa some 200,000 years ago (mitochondrial eve)