Upgrade to remove ads
Chapter 15. Immunology
Terms in this set (44)
study of the physiological defenses by which the body recognizes itself from nonself
1. protect against infection by microbes.
2. isolate/remove non microbial substances
3. destroy cancer cells that arise in body
2. vary in number, structure, and function
3. larger than erythrocytes
5 types of leukocytes
1. neutrophils (most numerous)
Where do the 5 types come from?
undifferentiated pluripotent stem cells
Innate Immune Defense
Non specific immune system
adaptive immune defense
specific immune system
-body surface defense
Types of Phagocytosis
cells involved with innate immunity
Types of Granulocytes (PMN)
1. local non specific response to tissue injury
bring phagocytes to invaded or area
-prepare subsequent healing and repair
T and B cells (adaptive)
Oldest immune system?
parasitic infection cell killers
important for allergic reaction
-bind to bacteria
-use pseudopods and engulf bacteria
-vacuoles get rid of bacteria
Sequence of immunity
-entry of microbe
-vasodilation of infected area
-increased capillary permeability
-chemotaxis through cytokines
chemical messenger that immune system uses to communicate
taxing in response to a chemical. "following the bacteria due to a smell"
Swollen Cut due to?
edema. and because the fluid from the blood (plasma and proteins) goes thru capillary into the interstitial fluid.
-monocytes and macrophages release endogenous pyrogen in response to bacterial molecules
-induces hypothalamus to increase body temperature
found in the body. causes hypothalamus to reset the thermostat.
decreases bacteria survival
Innate or Complement System
-cascade of events
-attacks the surface of foreign cells
-helps the other parts of the immune system
-systemic travel continuously thru body
-response due to recognition of specific antigen
any foreign molecule capable of triggering an ADAPTIVE immune response
colonal selection theory
-each lymphocyte specific for pathogen
-exposure to pathogen results in production of clones of disire (proliferation).
primary lymphoid organs
site of maturation:
Where do B cells mature?
Where do T cells mature?
Secondary lymphoid organ
site of encounter and activation:
2 classes of adaptive immunity
1. antibody mediated or Humoral immunity
2. cell mediated immunity
antibody mediated or humoral immunity
involves production of antibodies by B cells derivatives known as plasma cells
involves production of activated t cells
-directly attack unwanted cells
-help other cells of immune system
3 types of T cells
killer, regulatory, helper
another name for anti bodies
B Cell Receptors
surface plasma membrane receptor that binds to a specific antigen
What happens after the binding to an antigen
-differentiate into plasma cells secrete antibodies
-memory cells to enhance future responses
B cells need ____
helper T cells
Antibody mediated responses
-can directly bind and inactivate toxins or viruses
-link microbe to macrophages, complement
-stimulate other cells
antibodies mark the "antigens" invading the body
YOU MIGHT ALSO LIKE...
The Immune System
Lymphatic & Immune Systems
AP Bio - Lymphatic System
Quiz 6 Lymphatic System and Immune