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Oral Path Chapter 6 Disorders of Genetics and Inheritance
Terms in this set (15)
a collection of signs and symptoms that occur together and characterize a particular abnormality or condition
Trisomy on chromosome 21
Incidence higher with increased age of mother
Mentally challenged, heart defects, altered immune system, risk of leukemia
Fissured tongue, macroglossia (also seen in acromegaly-excess growth hormone)
mouth breathing, hypodontia
Taurodontism, periodontal disease, decreased caries (does NOT have xerostomia)
brittle bone disease
Multiple benign osteomas
Intestinal polyps at high risk to become malignant
Disorders of Enamel
Types of Amelogenesis Imperfecta
What are the 3 types of Amelogenesis Imperfecta?
What is Hypoplastic of Amelogenesis Imperfecta?
Incomplete or arrested development of enamel
Alters morphology and thickness of enamel
Clinically see enamel hypoplasia, pits, grooves, soft enamel, teeth can darken or be discolored
Radiographically enamel may be absent
Hypoplastic of Amelogenesis Imperfecta
What is Hypomaturation of Amelogenesis Imperfecta?
Enamel crystalline structure fails to mature
Enamel is malformed, soft, and porous
Enamel may appear mottled and opaque
Hypomaturation of Amelogenesis Imperfecta
What is Hypocalcified of Amelogenesis Imperfecta?
Appear normal upon eruption
Wear rapidly and are susceptible to caries
Hypocalcified of Amelogenesis Imperfecta
What is Dentinogenesis imperfecta?
Hereditary disorder of the dentin
Occurs alone or with osteogenesis imperfecta
Discoloration of teeth gives the name opalescent dentin
Abnormal roots and bulbous crowns
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