Immunology Exam 1
Terms in this set (22)
virus, bacteria, fungus, parasite
four main categories of pathogens
molecule recognized by the immune system
IS, blood, lymph, epithelial surfaces
Extracellular pathogens are located in ____________, ____________, ____________, and ____________.
cytoplasm, vesicles of cells
Intracellular pathogens are located in ____________ or ____________.
anatomic barriers, complement/antimicrobial proteins, innate immune cells, adaptive immuneity
list 4 levels of defense used to protect against pathogens
skin, oral mucosa, respiratory epithelium, intestine
list 4 anatomic barriers
C3, defensins, reglll gamma
list 3 complement/antimicrobial proteins
macrophages, ganulocytes, natural killer cells
____________, ____________, and ____________ are the innate immune cells.
B cells/antibodies, T cells
____________ and ____________ are involved in adaptive immunity.
Immunity that is present before exposure and effective from birth. Responds to a broad range of pathogens.
the ability to recognize and remember specific antigens and mount an attack on them
pattern recognition receptors (PRRs), pathogen associated molecular patterns (PAMPs)
____________ recognize common molecular patterns called ____________ that are part of many microorganisms, but are not present in the host and therefore are considered as non-self.
proteins that bind to and neutralize their pathogens or prepare them for uptake and destruction by phagocytes
Innate immune cells also express ____________ receptors that recognize antibody coated pathogens.
____________ immune cells express receptors that are specific for one type of antigen
antibodies, lymphocyte receptors (BCR, TCR)
____________ and ____________ recognize a particular type of foreign antigen.
immunological recognition, immune effector functions, immune regulation, immunological memory
list 4 functions of the immune response
the capacity to make quicker and stronger responses to successive encounters with antigen
epitope (antigenic determinant)
sites within antigens to which antibody, BCR or TCR bind
blood cell formation
white blood cell
subset of leukocytes-
NK cells (large)
B cells (small)
T cells (small)
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