Integrated Cardiopulmonary pharmacology chapter 11
Terms in this set (34)
Neruomuscular blocking agents
are used to facilitate endotracheal intubation at a one time dose
you become paralyzed. Ach cannot stimulate the muscle. prevents the motor endplate from depolarizing.
increase Ach levels
antidote for a nondepolarizers nuromuscualr blockade
examples: pancuronicum, rocuronium, vercuronium
cholinesterase block AchE
the second way to reverse nondepolarizing agents after increaseing Ach levels at recetor sites
short term,contract first then become paralyzed, are agonist that actaully bind to the Ach receptor and inititate a massive depolarization of the muscl
depolarizing neuromuscualr blocking agent that binds with cholinergic receptors and start depolarization by causing total body muscle contraction folled by muscle paralysis
do not affect pain or consciousness.
long duration nmba
Anectine or suc
depolarizing agent, gold standard for quick intubation, rapid onset, short duration.has been associated with malignant hyperthermia
requires no dosage for renal or liver impairment. has a metabolite, and produces histamine release, nmba
no histamine release nmba
skeletal muscle relaxants
relieve musculoskeeltal pain or spasm. used in patients with multiple sclerosis, spinal cord injuires and stroke. Example=Dantrolene Dantrium
decrease the force of the skeletal muscle contraction by stopping the release of calcium
any medication that induces sleep
any medication that reduces symptoms of anxiety
work by enhancing the blocking effect on the receptor for the neurotransmitter GABA. most common is midazolam (Versed)
alpha 2 adrenergic agonist. used in ICU for sedation of vent patients and for sedation prior to and or during surgical procedures
oldest, treat seizure, sleep, and anxiety disorders. used in overdose situations and cause respiratory depression, CNS depression and coma and death
inability to perceive sensations
has 2 characteristics: unconciousness, analgesia, muscle relaxation, and depression of reflexes
condition in which there is sustained skeletal muscle contracting that if untreated results in muscles breakdown and potential renal impairment
lipid soluble med that can be administered IV to induce and maintain general anesthesia. can cause a elevation of serum triglycerides.
sedative at low doses. used as an analgesic
most commonly known drug with local anesthetic properties. works by binding to the a membrane site that when stimulated results in the inability of the neuron to depolarize
drug that causes nervous system to arousal and increases the rate and depth of ventilaition
medroxyprogesterone is a progesterone hormone that stimulates alveolar ventilation and increases the body's response to hypoxia. used in the treatment of?
reduction in the sensation of pain
located in joints, fire before there is damage and serve in a protective role
palliative, quality, radiation, severity, and translates
state of adaption in which repeated exposure to a drug induces changes that result in a decrease of one or more of the drug's effects over time
one of the first analgesic meds. example=heroin. FDA heavily regulates these kinds of drugs.
opoid antagonist that reverses the CMS and ventilatory depression that can be caused by opoids. used in overdoses.
nonsteriod anti-inflam agents
NSAIDS are most common. are considered the drugs of choice in situation of tissue destruction pain