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33 terms

Blood Cancers buzzzzzzz

JAK2 mutation
polycythemia vera, essential thrombocytosis
t(14;18) bcl-2 gets translocated to Ig locus
follicular lymphoma
smudge cells
hairy cell leukemia
cyclin D1 gene overexpression
mantle cell lymphoma
follicular lymphoma transforms to this
Diffuse Large B Cell Lymphoma
auer rod
gingiva infiltration
asymptomatic M-spike
TDT positive
skin lesion variant
Acute T-Cell Leukemia Lymphoma
Birbeck granules
langerhans cell histocytosis
Philadelphia Chromosome
CML. (t9;22) BRC-ABL
punched out bone lesions, osteoporosis
Multiple Myeloma
CRAB organ damage
Multiple Myeloma - hypercalcimia, renal insufficiency, anemia, bone lesions
teardrop cells
primary myelofibrosis (aka chronic idiopathic myelofibrosis)
ALK gene rearrangements
Anaplastic Large Cell Lymphoma
horseshoe nuclei
Anaplastic Large Cell Lymphoma
middle ground between MGUS and Multiple Myeloma
Smouldering Myeloma
c-myc translocated to Ig locus (t8;14)
starry sky
chronic gut inflammation
marginal zone lymphoma
abnormally large and weird platelets
Essential Thrombocytosis
anti-CD20 antibody therapy works
follicular lymphoma
tons of small lymphocytes, few RS
lymphocyte rich classical Hodgkins
RS cells and varients on a mixed cellular background
mixed cellularity classical Hodgkins
few lymphocytes and lots of RS cells
lymphocyte depleted classical Hodgkins
fibrous nodular pattern + lacunar cells
nodular sclerosis classical Hodgkins
popcorn cells, nodularity, lymphocytes
Nodular lymphocyte predominant Hodgkin lymphoma
centrocytes and centroblasts
follicular lymphoma
lymphoid lineage
T Cells, B Cells(and plasma), natural killer cells
myeloid lineage
RBCs, monocytes, neutrophils, basophils, eosinophils, megacaryocytes