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FSCJ Dr. Davis A&P2 Test Bank Blood

Which is NOT a major function of the blood?

e. Production of oxygen

The normal average temperature of blood is around

b. 100.4 F

The normal pH range for blood is


Which of the following is not a component of blood?

c. Carbon dioxide

The hematocrit is composed of

c. RBC

How much of blood plasma is water (approximately)?

b. 91%

Which of the following plasma proteins plays a role in disease resistance?

b. Globulins

Which of the following plasma proteins plays a role in blood clotting?

c. Fibrinogens

A hemocrit measures

a. Percentage of RBC in packed blood

The process by which formed elements of the blood develop is called:

b. Hemopoiesis

A megakaryoblast will develop into

c. Platelet

During hemopoiesis, some of the myeloid stem cells differentiate into

a. Progenitor cells

This hormone stimulates proliferation of red blood cells in red bone marrow

a. EPO

How many hemoglobin molecules are in each RBC?

c. 280 million

Ferritin is used to

b. Store iron

A red blood cells function is

d. Gas transport

A Red blood cell without a nucleus is called a

e. Reticulocyte

Which of the following is a phagocyte?

a. Monocytes

Which of the following reduces blood loss?

b. Platelet

Which of the following promotes inflammation?

d. Basophil

Which of the following destroys antigen-antibody complexes?

a. Eosinophil

Which of the following destroys provides immune responses?

a. Eosinophil

Which of the following is not an agranular leukocyte?

d. Basophil

The process of a white blood cell squeezing between cells to exit the blood vessel is called

a. Emigration

Which of the following do mast cells not release?

c. Nitric oxide

This hormone causes the development of megakaryoblasts.

b. Thrombopoietin

Which methods provide hemostasis?

d. platelet plug formation, vascular spasm, clotting

Once this is formed, the intrinsic and extrinsic pathways are identical.

b. Prothrombinase

Which of the following clotting factors has the most to do with strengthening and stabilizing a blood clot?

d. FactorXIII

Considering Rh blood types, which of the below situations would result in maternal antibodies attacking the fetus?

b. Mom is Rh negative and fetus is Rh positive

Which of the following opposes the action of thromboxane A2?

e. Prostacyclin

Which of the following is an anticoagulant?

a. Heparin

List and briefly describe the functions of blood.

1) Transportation carries oxygen, carbon dioxide, nutrients, wastes, hormones and heat
2) Regulation helps maintain pH via buffers, body temperature via properties of water in plasma, and water balance via osmotic pressure created by plasma proteins 3) Protection via clotting, antibodies, phagocytosis, and complement

Describe the negative feedback loop that controls the rate of erythropoiesis. Under what circumstances would you expect the rate of erythropoiesis to be increased? How would it be possible to tell if the rate of erythropoiesis is elevated?

Hypoxia in the kidney leads to secretion of erythropoietin, which targets proerythroblasts in red bone marrow to mature into reticulocytes, which enter circulation to become red blood cells which increase the oxygen carrying capacity of blood. The rate of red blood cell formation should also be increased in any form of anemia (reduced oxygen carrying capacity of blood), or when oxygen levels in the external environment are low (e.g., high altitudes). High levels of reticulocytes in circulation indicate an increase in erythropoiesis.

Explain the proposed role of hemoglobin in the maintenance of blood pressure.

Hemoglobin releases carbon dioxide and nitric oxide when passing through the lungs. It then picks up oxygen and super nitric oxide, which are then circulated and released to tissues. Release of super nitric oxide causes vasodilation and so, a decrease in blood pressure. Nitric oxide causes vasoconstriction and an increase in blood pressure.

On a differential white blood cell count, Ezra is found to have 85 percent neutrophils and an elevated number of band cells. What is the most likely cause of Ezra's high neutrophil count? What benefits are being provided by all these neutrophils? What is the significance of the band cells?

High neutrophil count indicates bacterial infection (most likely), and increased band cells indicates a rapid turnover of neutrophils with an increased demand for replacements. Neutrophils are phagocytes that, upon engulfing a pathogen, release antimicrobial substances, such as lysozyme, oxidants, and defensins.

Why does damaged endothelium present an increased risk of blood clotting?

Blood may come in contact with collagen in the surrounding basal lamina, which activates clotting factor XII, which ultimately leads to the formation of fibrin clots. Platelets are also damaged by contact with damaged endothelium and begin their release reaction.

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