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15 terms

Metabolic Enzymes

Enzymes involved in vitamins, amino acid biosynthesis,
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Galactokinase + ATP
Galactose --> Galactose-1-Phosphate+ADP
Epimerase
UDP-galactose--> UDP glucose
Galactose-1-Phosphate Uridyltransferase
Galactose-1-phosphate--> UDP Galactose
Hexokinase+ATP
Fructose--->Fructose-6-Phosphate+ ADP
Fructokinase
Fructose--> Fructose-1-Phosphate
Aldolase B
Fructose-1-Phosphate--> DAP+ Glyceraldehyde
Acetaldehyde dehydrogenase (mito)
Acetaldeyhyde--> acetate
alcohol metabolism
Alcohol dehydrogenase (cyto)
Alcohol--> acetaldehyde
Deficiency: Flushing
Acetyl thiokinase (mito)
acetate--> acetyl coA
Disulfiram
Treatment for alcohol abuse
Inhibit acetylaldehyde dehydrogenase
Linolenate
Omega-3
PUFA
Essential fatty acid
Fish
Deficiency: Learning difficulties, impaired vision
Arachidonate
Omega-6
PUFA
Essential fatty acid
Seeds
Deficiency: Growth retardation, skin lesions, reprod failure, increased CVD
Bile salts
Fat droplets-micelles
Pancreatic lipase
Droplets--> TAG--> f.a + glycerol
Phospholipids--> lysophospholipid+f.a
Cholesterol esters--> cholesterol + f.a
HMG-CoA reductase
3 Acetyl-CoA--> Cholesterol