12 terms

Eukaryotes

Fungi
STUDY
PLAY
Moulds
Filamentous growth form comprised of hyphae
reproduce by spores
free living in environment
infection--> inhalation of spores
Yeast
Unicellular
reproduce by budding
commensal-opportunistic
effect skin, nails and mucous membranes
Dermatophytes
Obligate pathogens
Ringworm fungi
fungi affecting skin, hair and nails
Trichophyton, microsporum, epidermophyton
Dermatophytosis
keratinophilic mould
T interdigitale and T rubrum
Foot and nail infections
Skin lesions require _________ therapy
Scalp or nail infections ________ therapy
Topical, oral
Subcutaneous mycoses
Mould fungal spores
Mycetoma
candidosis
Yeast infection- Candida
commensal in mouth and GI
Cause: thrush, cutaneous nail infection
Vaginal c - pregnant women
Oral c- AIDS
Flucanazole
Treatment for candidosis
Cryptococcosis
encapsulated Yeast
treatment: flucanazole, flycytosine, amphotericin B
Aspergillosis
Mould in soil
A.fumigatus
Inhalation of spores
Spread in lungs especially neutropenia
CT scan-fungal infection
Treatment: Amphotericin B, voriconazole, posaconazole and caspofungin
Mucormycosis
Mould
Spoiled food
Cutaneous infection- contamination of wound
necrtoic infarction
Amphotericin B