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8 terms

Osteoarthritis

STUDY
PLAY
Increase matrix synthesis
TGF-B
IGF-1
Increase matrix resorption
IL0-1
TNF
Heberdens node
Node at the DIP joint
Douchard's node
Node at the PIP joint
Pathogenesis
Osteophytes
Worn cartilage
Loose ligaments
Changes in bone
Narrow joint space
marginal osteophytes
Sclerosis
Eburnation
Focal pressure necrosis and subarticular cysts
Clinical features
Crepitus
swelling
muscle wasting
warmth
bony swelling
symptoms
use related pain
joint stiffness after inactivity
reduced range of motion