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Terms in this set (13)
What is the class of epi?
What is the trade name of epi?
What is the mechanism of action of epi?
direct-acting alpha and beta agonist
What is the mechanism of epi as a alpha agonist?
What is the mechanism of action of epi as a beta-1 agonist?
positive inotropic, chonotropic, and dromotropic effects
What are the mechanisms of action of epi as a beta-2 agonist?
bronchial smooth muscle relaxation and dilation of skeletal vaculature. Blocks histamine receptors
What are the indications of epi?
-pulseless electrical activity
-heart blocks, bronchospasms, and anaphylaxis
-pulseless ventricular tachycardia
What are the contraindications of epi?
What are the adult doses of epi?
-v-fib, pulseless v-tach, PEA and asystole: 1mg, of 1:10,000 repeated every three to five min
-asthma and anaphylaxis: 0.01mg/kg IM (0.5mg max single dose 1:1,000)
-anaphylactic shock: 1mg of 1:1,00 in 250 NS started at 2-10 mcg/min and titrate to desired effect
-symptomatic bradycardias 2-10mcg/min
-ROSC 0.1-0.5 mcg/kg/min
What is the pediatric dose of epi?
-resuscitation dose: 0.01mg/kg IV/IO refer to broselow tape
-asthma and anaphylaxis 0.01 mg/kg IM (0.3 mg max single dose 1:1,00)
-anaphylaxis, ROSC, and other hypoperfusion states 1mg of 1:1,000 in 250 NS started at 0.1-1mcg/kg/min and titrate
-symptomatic brady 0.01 mg/kg IV/IO refer to Broselow tape
What is the route of epi?
IV, IM, IO, AT
What are the precautions of epi?
-give cautiously in patients with hypertension, tachycardia, or who are prentant
-do not mix with sodium bicarbonate, deactivates epi
What are the adverse reactions of epi?
-tachycardia, palpitations, anxiety and headache
-inreased myocardial oxygen demand
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