New Drugs

Terms in this set (45)

Plan B two pill

brand no longer marketed- generic
17+
7% use it right

Plan B one step

$50
no age restrictions
Teva has 3 year exclusivity

3x greater risk of obese women getting pregnant with morning after pill
165lbx + may want to consider copper IUD

doesn't actually exist
lidoderm patch claims it may be confusing since it's not the same product

polymer matrix to prevent extraction of methamphetamine
still behind counter

has no medication
just covers

overactive blader in WOMEN 18+
new patch every 4 days

oxytrol otc indications

urinating 8x or more per day
urgent need to urinate
not able to control the urge

oxytrol OTC effectiveness

reduced frequency by one episode a day

asthmanefrin (racepinephrine)

4yo and up
alternative to primatene mist
no CFC or preservatives

asthmanefrin counseling

don't touch with mouth
clean each night with vinegar for 3 minutes
no more than 2d/w; wo MD
go to ER if SOB after 20 minutes

What drugs just made the RX OTC switch?

nexium (esomeprazole)
nasacort AQ (triamcinolone acetonide)

2 yo +
nasal allergy sx

hydrocodone reclassification

Schedule III but petition out to make it CII

Tylenol combo products

recommendation to no longer have products over 325mg

ER hydrocodone
severe pain, ATC long term opiate needs
not for PRN

working on a tamper proof system - right now you can easily get yourself dead from it

ER/LA opioids labeling

BBW - neonatal opioid withdrawal syndrome
indicated for pain severe enough to require daily, ATC longer term opioid tx for which alternative therapies are inadequate

naloxone HCl injection
opioid OD
0.4mg/mL prefilled auto injector

AHA guidelines 4 groups of pts

CV disease
LDL 190+
DM2 and between 40-75 yo
10 year CVD risk 7.5% or higher and 40-75 yo

New AHA guidelines effect

31million new people on statins
guidelines are new

high blood pressure
2014
same staging as JNC 7

18-59 including DM and CKD <140/90
>60 yo <140/90
>60 <150/90 - relaxed and controversial

JNC 8 recommendations

BB no longer recommended for BP control
split panel on 2 drug combo

AFib new significant recommendations

increased use of radio freq ablation in tx of nonvalvular AF
novel oral anticoagulants
diminished role of ASA
endorse CHA2DS2-VASc

added vascular dx, age, sex
gave age an extra point
more predictive - esp in older women

dabigatran
lower risk of clot related strokes, bleeding in brain, and death than warfarin
inc risk of major GI bleed
MI risk similar

dapagliflozin 5 & 10 mg
CI in severe renal impairment <60
lowers A1C by 0.8-0.9

SGLT2 inhibitor - reduces reabsorption of filtered glucose - lowers renal threshold for glucose - increases glucose excretion

inc LDL
female genital mycotic infections
nasopharyngitis
UTI

rosiglitazone
non inc heart attack - poor Dunbar
REMS will be modified

ambien
lower dose for the women folk
from 10mg - 5mg
from 12.5 to 6.25 ER

doxylamine succinate and pyridoxine HCl 10/10
morning sickness

diclegis directions

take 2 tabs in the evening on an empty stomach
may add 3rd on day 3
may add 4th on day 4 midafternoon

very expensive
try to do non pharm stuff first

fluticasone/vilanterol
inhaled corticosteroid/LABA
COPD

Breo Ellipta counseling

1 inhalation
opening cover activates - lose dose if you close without taking it
expires 6 weeks from removal of pouch

Breo Ellipta BBW

LABA increase risk of asthma related death and should not be used as rescue therapy

umeclidinium LAMA and livanterol LABA
COPD
one inhalation daily

dalbavancin injection
acute bacterial skin and skin structure infections ABSSSI caused by Gram +
covers MRSA and MSSA

two dose regimen
1000 mg IV x1 dose over 30 mins
following week 500mg IV x 1 dose infused over 30 mins

Trials for dalvance

Discover 1 and Discover 2
non inferior

dalliance class

2nd gen semi synthetic lipoglycopeptide

generating Abx incentives NOW
passed 2012
granted priority review as QIDP

qualified infectious disease product

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