ALL Acute lymphocytic leukemia
Of acute leukemias, the most responsive to tx
AML Acute myelogenous Leukemia
Worst response to tx of all
CLL Chronic lymphocytic leukemia
Abnormally small lymphocytes
Lymphoid tissue in blood
CML Chronic myelogenous leukemia
Middle-aged adults. Rare in children
Caused by carcinogenic chemicals and radiation
+Granulocytic precursors (myeloblasts and promyelocytes)
Autoimmune Hemolytic anemia
IgG antibodies combine w/ RBC surface antigens
Antibody coated RBC are sequestered in the spleen (where hemolysis occurs)
Mother's antibodies attack fetal RBCs when different Rh factor
Sickle cell anemia
Inherited autosomal recessive
Abnormal type of hemoglobin Hb-S
Valine substituted for glutamic acid in the sixth position
Lack of intrinsic factor
B12, necessary for RBC formation, is not absorbed in the GI tract because of the lack of IF
Stomatitis and glositis
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