6 parts of non-specific immunity
external barriers, phagocytosis, inflammation, natural killer cells, fever, interferon & complement
3 external barriers
epithelial linings - acidity, dead surface cells, flakes off.
hair follicles, sweat glands
mucosa and cilia
5 internal barriers
phagocytosis & chemical release, inflammation, killer cells, fever, interferon & complement.
when a leukocyte, a.k.a. white blood cell (neutrophil, monocyte, eosinophil) encapsulates and consumes and antigen.
later responders. produce toxic chemicals. elevated levels in chronic infection.
antigen presenting (def.)
the 3 phagocytic cells consume the antigens and then regurgitate/display the antigen markers, so that the T- and B-cells can recognize - thus triggering adaptive immunity, or specific defense.
Inflammation response (3 parts)
release of chemicals (histamine for vasodilation)
isolation of damaged areas (fibrinogen)
lymph drainage (takes antigen into lymph nodes)
macrophages release chemicals targeting the hypothalamus to raise body temperature to help fend off bacteria and virus.
Action of interferon (4 things)
'warns' other cells, inhibits virus from multiplying, contains virus until specific immunity can take action, stimulates lymphocytes to attack and kill infected cells.
a surface-bound enzyme in our cells. can cause invading cell to rupture. Causes vessel dilation, and enhances inflammation.