any chemical used for therapeutic application for treating an illness, symptom, or for diagnostic testing.
pure undiluted for of the chemical or ingredient that produces an effect
affect or assist the drugs action by adding flavor, bulk, color
causes no harmful effects when taken over a long period of time
the origin of drugs
how the body processes drugs, what the body does to the drug absorption-movement of a drug from it's sit eof administration into the blood distribution-movement of a drug from the blood into the tissues metabolism-chemical alteration of the dug in the body excretion-removal of waste products of drug metabolism from the body
drug actions on the body (what the drug does to the body)
the effects of drugs in the treatment of disease
the poisonous effects of drugs on the body
Medication adminstered routes
enterally-directly into GI system by oral, rectal, or nasogastric tube parenterally-intradermal or subcutaneous, IM, or IV (inections_ percutaneouly by inhalaing, sublingually, transdermally or topically.
it's ability to disolve
free or unbound drug
once drug has reached the blood stream and is ready for use by the body
factors that cause variation in absorbtion rate
incorrect administration, ph, absence or presence of food in stomach, fat or lipid solubility, length of contact, inhalation factors, drug concentration
steps used to process drugs
absorption, distribution, metabolism, excretion. dependent of age, mental state, route of admin, gener and phy condition of the patient.
time in which half of the initial dose has been metabolised.
occurs most commonly via kidneys
total body effect of a drug that is absorbed into the bloodstream
limited to the site of admin and the tissues immediately surrounding (nose spray)
effect of a drug on the body at a distant site from admin.
reduces the activity of the body part
increases body functin of activity (laxitives)
produces inflammation at site application (Efudex irritates skin for destructin of a lesion)
soothing action for an irritation (hydrocortisone for skin reaction)
testing to pinpoint disease
replace missing chemicals
avoidance of deficiences or to reinforce existing body chemicals
prevent of lessen the severity of a disease
reduce the symptoms of a disease but not treat the disease or condition
kill or remove the causative agent of disease
maintain a conditin of health put at risk by a disease (insulin for diabetes)
maintain the body in homeostasis until disease process can be resolved (oxygen therapy
mild, responses to medications
imply problems or symptoms more severe than side effects, undesirable and unpredicable