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usmle world 24

Terms in this set (103)

germ cell tumor
15-30 yo (peak of reproduction) ->ovarian tumor.
benign surface epithelium
cystadenoma
30-40 (premenopausal but past prime)->ovarian tumor
malignant surface epithelium
cystadenocarcinoma
postmenopausal women->ovarian tumor
queyrat erythroplasia
glans->squamous cell carcinoma precursor lesion
bowen disease leukoplakia
penis shaft->squamous cell carcinoma precursor lesion
bowenoid papulosis
reddish papules on skin of penis->squamous cell carcinoma precursor lesion
Diffuse large b cell lymphoma
bilateral Testicular Cancer in a male > 60yo
tamsulosin
terazosin or tamsulosin?
selective alpha 1a antagonist for BPH in a normotensive patient
terazosin
terazosin or tamsulosin?

alpha 1 antagonist for BPH in conjunction with hypertension
posterior periphery
Prostatic adenocarcinoma->what region of prostate?
10ng/dl
A PSA of what is worrisome of prostate cancer at any age?
1-4ng/dl
PSA increases with age. What is the normal range?
bound PSA
free PSA↔bound PSA

Which does cancer tend to make?
architecture
Nuclear atypia or architecture?
Prostate adenocarcinoma gleason grade
lumbar spine
Where does prostate cancer spread?
Prostate adenocarcinoma
?->Osteoblastic metastasis->sclerosing bone lesion
lateral forearm
Sensory: c5-c7 musculocutaneous nerve
c5-t1 radial
Sensory posterior arm?
c5-t1 radial
Sensory posterior forearm?
c8-t1 ulnar
sensory medial forearm?
c5-7 musculocutaneous
arm flexors
nerve?->+sensory lateral forearm
↓
motor?
external carotid
maxillary
pterion
1) artery->2)artery->middle meningeal artery=
3)under what part of the skull?
ACE inhibitor
ACE inhibitor or Thiazide?
LONG TERM control of Hypertension in a patient with CHF
myosin
actin or myosin?
Phosphorylated->Contraction
s2-4 pudendal
ischial spine
What nerve is blocked during labor?
What is the landmark?
l2-4 genitofemoral
sensory: scrotum
l2-4 genitofemoral
sensory: labia majora
l2-4 genitofemoral
sensory: femoral triangle skin
t12-l1 iliohypogastric
sensory: iliac crest skin
CNIX
sensory: tympanic membrane inner surface
CNIX
sensory: upper pharynx
CNIX
sensory: middle ear cavity
inferior salivatory
CNIX
Otic
Parasympathetic Nucleus->nerve->ganglion->
parotid secretion.
Nucleus?
Nerve?
Ganglion?
superior salivatory
CNVII
Submandibular
Parasympathetic Nucleus->nerve->ganglion->
submandibular gland secretion.
Nucleus?
Nerve?
Ganglion?
superior salivatory
CNVII
Submandibular
Parasympathetic nucleus->nerve->ganglion->
sublingual gland secretion.
Nucleus?
Nerve?
Ganglion?
CNXII
Motor: tongue protrusion
CN IV
diplopia when walking down stairs or reading newspaper.

Where is the lesion?
K+ sparing diuretic
Amiloride
thiazide diuretic
indapamide
ergonovine
prinzmetal angina
drug→+5HT2=Gq
↓................↓
+alpha1→corovary artery vasoconstriction=?
atrial natriuretic peptide
protein→localized cardiac atrium amyloidosis
prolactin
protein→localized pituitary amylodosis
beta amyloid protein
protein→localized cerebral vessel amylodosis
amylin islet amyloid protein
protein→localized pancreas islet amyloidosis
calcitonin
protein→localized thyroid amyloidosis
Fenoldopam
D1 Gs
Drug?
↓
receptor?→XSevere Emergency Hypertension
↓
Increased renal perfusion via dilation
CD43
X linked Wiskott Aldrich
T cell/Platelet
↓
1)?=actin filament→microvescicle
↑
X 2)?
mannose 6 phosphate
LYST
chediak higashi
Phagocyte→Golgi→lysosome protein-1)tag?
→2)shuttle protein→lysosome→bacteria lysis
.......X
.......↑
3) disease?
ataxia telangiectasia
B cell→cell cycle kinase→+cell cycle
................X
................↑
...............?
HSP
Hemolytic Uremic Syndrome (HUS) or Henoch Schonlein Purpura (HSP)?
joint pain
clindamycin
metronidazole or clindamycin?
Covers anaerobes AND S. pneumoniae
trazodone
antidepressant->priapism
TCA
amoxapine
t(11;14) mantle cell lymphoma
CLL/SLL
c myc burkitt lymphoma
Bcl5 Germinal Center B cell DLBCL
t(14;18) follicular lymphoma
BCL10 Marginal Zone lymphoma
CLL/SLL
BCR signal Activated B cell DLBCL
multiple myeloma
glucuronosyl transferase
OATP1b1
fibrate
superficial inguinal
calf
popliteal
Lymph drainage: skin inferior to umbilicus including anus inferior to dentate? What area is the exception? Where does it drain?
abdominal aorta nodes
Lymph drainage: testicles
internal iliac
external iliac
sacral
Major site of prostate lymphatic drainage?
Minor site?
external iliac
Lymph drainage: superior portion of bladder
internal iliac
Lymph drainage: inferior portion of bladder
inferior mesenteric
Lymph drainage: sigmoid colon
ulnar
ulnar or median nerve?
hypothenar
HDL
+LCAT cholesterol esterification
ApoA-I
Particle:
Function:
chylomicron
enterocyte chylomicron synthesis
ApoB-48
Particle:
Function:
LDL
Extrahepatic LDL uptake
ApoB-100
Particle:
Function:
Chylomicron
HDL
LPL activation
ApoC-II
Particle:
Function:
chylomicron/VLDL
hepatic particle uptake
ApoE-3&4
Particle:
Function:
body touch
VPL
?→medial lemniscus→thalamic nucleus?
VPM
Face Pain/Temp; Face touch→CNV→thalamic nucleus?
vision
Lateral geniculate thalamus
hearing
medial geniculate thalamus
VPM
insula
Parietal operculum
Taste→thalamic nuclei?→cortex area?
chorda tympani CNVII
Nerve: Anterior 2/3 tongue Gustatory
CNIX
Nerve: Posterior 1/3 tongue gustatory
CNX
Nerve: Posterior area tongue root
CNV3
Nerve: P+T and Touch anterior 2/3 tongue
CNIX
Nerve: P+T and touch posterior 1/3 tongue
CNX
Nerve: P+T and touch posterior area tongue root
palatoglossus
CNX
What is the one tongue muscle not innervated by CNIX? What nerve?
phrenic nerve
Nerve: sensory mediastinal+diaphragmatic pleura
posterior cord c6-8 thoracodorsal
Nerve: latissimus dorsi
C5 dorsal scapular
Nerve: rhomboid major
c6-7 subscapular
Nerve: teres major
c5-7 long thoracic
Nerve: serratus anterior
c5-t1 recurrent branch median
c8-t1 deep branch ulnar
Nerve damage->X finger abduction
c8-t1 deep branch ulnar
nerve damage->X thumb adduction
L5-S2 inferior gluteal
gluteus maximus
X nerve -> X muscle ->
X climbing stairs/rising from seated position
L4-S1 superior gluteal
gluteus medius/minimus
X nerve->X muscle->
patient leans toward unaffected side in gait and standing on foot of affected side.
diazoxide
drug
↓
+k+ channel=hyperpolarize
......................↓
......................X Ca2+ channel=VasoDilation
hydralazine
drug→X IP3→X SR Ca2+=vasoD
↓
+Ca2+ activated K+ channel
↓
hyperpolarization→X Ca2+ channel=VasoD
marijuana
Illicit drug use->conjunctival injection (red eye)
PCP
Illicit drug use->nystagmus+ataxia
ketamine
Illicit drug use->hypersalivation
gamma hydroxybutyrate
psychadelic drug->X memory storage
5HT2 Gq
Illicit drug use->receptor?->hallucination
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