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Pathology Labs - Text/notes
this set is complementary to the other two lab sets
Terms in this set (27)
which type of thyroiditis more commonly ends in atrophy?
which type of thyroiditis causes a more progressive destruction?
the most common manifestation of thyroid dz?
residual thyroid tiss in hasimoto appears (eosinophilic/basophilic)? and that's bc?
hurthle cell change-abundant mitochondria
in hypothyroidism/iodine deficiency, when the effect of TSH disappears in a certain area, the follicles appear?
"colloid nodule" = colloid > cells
dilated follicles & cells will become flattened
<area will not become hyperplastic>
"multinodular goitre" = colloid nodules + other hyperplastic areas
a multinodular goitre is "toxic" when?
the hyperplastic nodules become independent of TSH
in graves, colloid most close to epithelial cells have a characteristic structure which is? why?
scalloped/moth eaten colloid
high turnover rate
Anaplasia...severe pleomorphism, bizarre nuclei, too many mitoses, abnormal mitoses
what distinguishes a parathyroid adenoma from hyperplasia histologically?
an adenoma compresses the surrounding rim
cell arrangement in parathyroid adenoma?
pit adenoma vs normal
loss of reticulin framework
Craniopharyngiomas are remnants of what?
(a suprasellar mass)
craniopharyngioma age distribution?
bimodal -> children & >60 yo
cranipharyngioma mainly presents with?
visual disturbanes due to compression of the optic chiasm (bitemporal hemianopsia)
craniopharyngioma can cause _____________ in children
growth retardation (low GH & hypopituitarism)
2 main types of craniopharyngioma?
adamantin o matous (children)
extra note: meaning of "adamantine"
firm zy diamonds, incapable of being broken
thussssssssssssssssssssssss calcification is common & there's some wet keratin that the papillary type lacks :o
adamantinomatous craniopharyngioma features
-cysts w/ cholesterol-rich yellowish material resembling machine oil (seen grossly)
-compact lamellar wet keratin (seen microscopically)
papillary cranipharyngioma features
craniopharyngioma by definition is (benign/malignant)
craniopharyngioma malignant transformation
SCCa (v rare tho; associated w/ irradiation)
islet cell tumour nuclei characteristics?
salt n pepper (similar to carcinoid)
normal adr gl
atrophic adrenals causes:
exogenous steroids (low ACTH)
addison's (chronic adr insuff.)
hypertrophic adrenals causes:
ACTH oversecretion ie cushing dz
adrenocortical carcinoma is dicovered at a(n) _______ stage? bc?
an advanced stage
retroperitoneal space permits great enlargement
note: an adenoma cannot enlarge as much
THIS SET IS OFTEN IN FOLDERS WITH...
Pathology Lab #1
Pathology Lab #2
Anatomy lecture 2, embryology part only
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