Muscle to bone. Fuse w bone periosteum
Fibers in fasciculus. Muscle cell
Fibers in fibril.
Fibers in myofibril. Actin and myosin
Small to large muscle formations
Filaments myofibril fibril fasciculus muscle
Repeating pattern of actin and myosin.
Protein fiber holds actin in place. Missing in md patients
Missing dystrophin, genetic, muscles atriphy. Duchenne- sex linked form
Muscles increase in diameter
Protein that bonds to oxygen
Tear and produce more myofibrils. Increases myoglobin hypertrophy mitochondria and capillaries
Organ damage, increase cholesterol, atherosclerosis, sad, violent, delusional
Muscle needs for contraction
Nervous stimulation, ph, oxygen, ca, energy
Motor neuron and its controlled fibrils
Place where motor neuron enters the muscle
Space between neuron and muscle
High o levels. 1 glucose makes 36 atp. 1 fatty acid 17 atp
2 cellular respiration
1 glucose yields 2 atp. Low o. Yields pyruvic acid-lactic acid
Lock up after death, sever atp depletion
Creatine/phosphate, glycogen in liver, fatty acid
2 factors of muscle performance
Conditioning and genes
Weight lifters, less vessels myoglobin o mitochondria atp
In between fast and slow
Acetylcholine, calcium ions diffuse, ca removes inhibiting protein from actin exposing active site, atp makes myosin crossbridge cock, 2nd atp breaks bond
Passive. Atp break bonds, ca actively transported back to sarcoplasmic reticulum,
Contracture, not enough atp to break bond
All or none law
Single muscle fibril will always completely contract or not at all with threshold
Proper neurotransmitter stimulus for contraction
Clostridium botulinum, prevents release of acetylcholine, paralyze muscles-diaphram
Cause rigidity, lockjaw. From puncture would w spores
Virus attacks neurons, paralyze leg and respiratory.
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