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each of the two new double helices of DNA will have one new strand and one old strand of DNA
the strand created by DNA polymerase III adding nucleotides to the complementary strand
enzyme that untwists the double helix at the replication fork, separating the two parental strands and making them available as template strands
single-strand binding protein
after the helicase separates the two parental DNA strands, this binds to the unpaired DNA strands, stabilizing themuntil they serve as templates
DNA polymerase I
removes the primer from the 5' end of the second fragment, replacing it with DNA nucleotides that it adds one by one to the 3' end of the third fragment
nucleotide excision repair
when DNA is repaired through the usage of the enzymes DNA polymerase and ligase
an enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells, thus restoring their original length
Beadle and Tatum
looked at neospora (bread mold) and deduced the one gene- one enzyme hypothesis (now false)
What was the hypothesis that expanded the one gene- one enzyme hypothesis?
one gene- one polypeptide hypothesis
genetic instructions for a polypeptide chain that are written on DNA in a series of 3 nucleotide words
pries 2 DNA strands apart and hooks together the RNA nucleotides as they base pair along the DNA template
collection of proteins that mediate the binding of RNA polymerase and the initiation of transcription
transcription initiation complex
assembly of transcription factors/ RNA polymerase II is bound to the promoter
alternative RNA splicing
a number of genes are known to give rise to 2 or more different polypeptides
messenger RNA (mRNA)
carries information specifying amino acid sequences of proteins from DNA to the ribosomes
signal recognition particle RNA (SRP RNA)
component of signal recognition particle, the protein- RNA complex that recognizes the signal peptides of polypeptides to the endoplasmic reticulum
small nuclear RNA (snoRNA)
aids in processing of pre-RNA transcripts for ribosome subunit formation in the nucleolous
base pair substitution
replacement of one nucleotide and its partner with another pair of nucleotides
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