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Pharm test #2
Terms in this set (11)
CNS stimulants are...
Cerebral stimulants, medullary stimulants, and spinal cord stimulants
CNS depressants are...
Nerve sedatives (tranquilizers), hypnotics (anticonvulsants), anesthetics (analgesics)
What is the blood brain barrier?
It is formed of capillary endothelial cells connected by tight junctions that do not exist in normal circulation
What does the blood brain barrier allow through?
Water, some gases, lipid soluble molecules, glucose and amino acids that are crucial to neural function
What effects happen when a drug is taken chronically?
Increased therapeutic effects, decreased side effects, tolerance and physical dependence
What suppressed pain by blocking sodium channels, thereby blocking impulse conduction along axons, only in neurons located near the site of administration and suppressed pain without generalized depression of nervous system?
Local anesthetic (-caine)
Why do you use local anesthesia with vasoconstrictors?
Prolong anesthesia (Epi), reduce the risk for toxicity - slow absorption
What are some local anesthetics?
Lidocaine, procaine, cocaine
What is the use of lidocaine?
Widely used, amide type, topical use and injection
What is the use of procaine (Novocain)?
Ester type, decline in dental use
What is the use of cocaine?
Intense vasoconstriction (tachycardia and hypertension), blocks norepinephrine reuptake
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