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substance is secreted regardless of secretorstatus. Even those who are sese, nonsecretors, willsecrete this Lewis substance into body fluids.
-Generally produced by Le(a-b-) individuals and are
frequently detected during antibody screening.
-are considered naturally occurring since they
appear without previous exposure to antigen positiveRBCs.
-Normally are IgM
Most are IgM while some IgG does exists (doesn not fix complement)
This antibody is generally not as common or as
strong as Lea.
Lewis antigens (significant)
Lewis antigens have receptors to certain
microorganisms like Helicobacter pylori
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