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Impairments & Disabilities Chapter 20
Terms in this set (47)
"is a tumor of endothelial cells. It occurs in middle-aged adults and is most often located on the head and neck."
is composed of smooth muscle cells and probably originates from smooth muscle cells of the blood vessels.
the second most common sarcoma of adulthood, is composed of malignant fat cells.
a highly malignant tumor originating in the soft tissues of extremities, usually occurs in young adults
originates from striated muscle cells, is the most important soft tissue tumor of children
malignant soft tissue tumors
benign nerve sheath tumor in the peripheral nervous system
A benign tumor of striated muscle
A benign tumor composed of fat cells.
A benign connective tissue tumor composed of fibroblasts
Tumor tissue mass resulting from abnormal cells.
Immune-mediated disease characterized by the formation of noncaseating granulomas.
Systemic lupus erythematosus
A systematic autoimmune disease caused by circulating immune complexes and most often affecting the skin, joints, and kidneys.
The lilac blue rash...of the upper lids is a helpful diagnostic finding (this disorder).
an immunologic muscle disease affecting several muscle groups.
This toxin causes spastic contractions of all muscles, even those at a distance from the site of infection...invariably lethal...there is no treatment...it is essential that everyone be immunized against (this) toxin early in life. A booster dose of vaccine is given every 10 to 20 years.
an important complication of wound infections marked by necrosis of muscles and formation of air bubbles in the tissues.
muscle disease "caused by bacteria, viruses, protozoa, or worms
inflammatory muscle diseases
An immunologic muscle disease affecting several muscle groups.
muscle deterioration as a result of the vascular, neurogenic, and metabolic changes occurring in diabetes
Neurogenic muscle atrophy
muscle deterioration as a result of a nerve problem
muscle weakness secondary to rheumatoid arthritis
nonspecific muscle weakness secondary to some identifiable disease
The most common form of muscle weakness in children...Neurogenic atrophy of muscles impairs the ability of the child to move. Many children are confined to a wheelchair and develop secondary deformities...Congenital weakness or paralysis of muscles resulting from ...brain damage.
group of diseases that comprise a slew of rare disorders, including inborn errors of lipid metabolism (e.g. carnitine deficiency) and glycogen metabolism, characterized by multisystemic involvement.
muscles can contract...but they remain contracted for some time...they cannot relax immediately.
second most common genetic muscle disease. It is inherited as an autosomal dominant gene; thus, it affects males and females at the same rate. The symptoms appear in adulthood. Muscle wasting is relentless and is typically associated with mental deterioration and diabetes. Frontal baldness and testicular atrophy are seen in men... characterized by myotonia...Premature death (usually in the fifties) is attributable either to complications of diabetes or to heart disease
Muscle disease causing mild face and shoulder weakness, may be associated with hypertension.
Muscle disease causing moderate shoulder girdle muscle weakness may be associated with cardiomyopathy.
ten times less common than Duchenne-type dystrophy...a mild form of...dystrophy...The symptoms of Becker's dystrophy appear later in life and are generally milder...the disease has a progressive course, and all patiend die in their late forties or fifties.
Duchenne-Type Muscular Dystrophy
the most common muscular dystrophy, caused by a deficiency of dystrophin, an integral plasma membrane protein...Skeletal muscle cells degenerate and muscle weakness ensues...a sex-linked recessive disease; it occurs only in boys...by the age of 10 to 12 years, these boys are confined to a wheelchair... ( death) usually occurs in late teens or early twenties. The mothers, who are the carriers of the gene, are asymptomatic.
"a group of muscle diseases, all of which show the following:
• Genetic defects inherited as Mendelian traits
• Primary muscle cell pathology
• Progressive course and symptoms related to muscle wasting"
tumors of the thymus
autoimmune disease involving the neuromuscular junction...characterized by impaired neural impulse transmission...rare disease with a prevalence of 1:10,000...more common in women...most affected women are 20 to 35 years of age...whereas men are generally older (50 to 60 years of age). ..associated with enlargement of the thymus...characterized by easy fatigability and muscular weakness...small extraocular muscles and facial muscles are most often involved. In 20% of affected patients, the disease remains limited to the eye muscles.
paralysis of one side of the body
paralysis of both legs
most common cause of neurogenic atrophy of the skeletal muscles
muscle cell atrophy caused by injury of the nerves
irregular and uncoordinated contraction of groups of fibers)
inability to sustain action
inability to contract adequately
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