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attaches ____ side chains to proteins and lipids from ER for targeting into the transport vesicles destined for specific destinations
Proteins that enter vesicles that leave the ER is a selective process mediated by ____
step 1 homotypic membrane fusion
NSF pries apart identical pairs of v-SNARES and t-SNARES in both membranes
step 2 homotypic membrane fusion
matching v-SNARES and t-SNARES from adjacent identical membranes interact
step 3 homotypic membrane fusion
membranes from both vesicles fuse to form vesicular tubular cluster
vesicular tubular clusters
____ can release COPI-coated vesicles which return resident proteins to the ER
ER retrieval signals
__ from escaped resident ER proteins binds to COPI coats for return to the ER
modifications to oligosaccharide
1. Man = Mannose 2. GlcNAc= N-acetylglucosamine 3. Gal=galactose 4. NANA=N-acetylneuraminic acid
vesicular transport model
golgi apparatus is a static structure while the molecule in transit move through the cisternae sequentially via transport vesicles
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