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Frederick Griffith's major contribution
transformative factor in bacteria; some chemical compound in cells must be responsible for BACTERIAL TRANSFORMATION
Steps of replication
1) Helicase unwinds and unzips
2) DNA polymerase adds new nucleotides
The ENZYMES are Helicase and Polymerase
Three types of Replication Models
Conservative (old strands stay together)
Dispersive (mix of old strands and new strands)
Semi-Conservative (1/2 old strands & 1/2 new strands)
In DNA, the fit between thymine and adenine and the fit between cytosine and guanine (A=T, C=G)
Main enzyme in DNA replication that joins individual nucleotides to produce a new strand of DNA, proofreads each new DNA strand to make sure that each molecule is a copy of the original
What did Hershey & Chase study?
they studied a bacteriophage that was composed of a DNA core and a protein coat
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