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Terms in this set (99)
What do natural penicillin treat?
Syphillis and strep.
What are your antistaph. Penicillin? "Say no to staph"
Nafcillin and oxocillin
What does nafcillin and oxocillin treat?
Adverse effects of nafcillin and oxocillin?
Hepatic dysfunction, neutropenia, thrombocytopenia
What are your aminopenicillin? ""AAs"
Amoxicillin and ampicillin
What does amoxicillin and ampicillin treat?
Entericocci, enteric GNRs
What's DOC for URTI, otitis media, and UTI in pregnancy?
What's DOC for susceptible GNRs, enterococci, streptocci?
What isyour anti-PSA penicillin?
What does piperacillin treat?
What are your beta lactamase inhibitor combos?
What do beta lactamase inhibitor combos treat?
What does piperacillin/tazobactam treat specifically?
Which beta lactamase inhibitors cannot treat atypical pneumonia? Which one is the drug of choice?
Ampicillin and piperacillin ; amoxicillin for URTI
What are your 1st generation cephalosporin?
What are 1st gen cephalosporin good for?
MSSA ( alternative to anti-staph penicillin [nafcillin, oxocillin]
What are your second generation cephalosporin ?
What are second gen cephalosporin used for?
Enteric GNRs, aneorobes
What are 3rd gen cephalosporin?
What are third gen cephalosporine good for?
What is ceftriaxone good for?
What is ceftazidime good for?
Why is ceftriaxone popular?
Because it is 1x per day dosage
What is your 4th gen cephalosporin?
What is cefepime good for?
What is an adverse effect of cefepime?
Can cause neurotoxicity, so may need to dose adjust
What is your 5th gen cephalosporin?
What is ceftaroline used for ?
MRSA and e. Faecalis
What are your cephalosporin/Blactam inhibitor combos ?
Cephtolazone/tazobactam (the BOMB for pseudomonas)
What is cephtolazone/tazobactam or ceftazidime/avibactam used for?
Multi drug resistant pseudomonas and CRE (carbapenem resistant )
What are your carbapenems? (MEDI)
What are Adverse effects of imipinem?
What are carbapenem treating for?
ESBL-producing GNRs (enterobacterias)
Should you use carbapenim for community acquired infections?
No; because they are very broad spectrum agents
What is your monobactams
What are monobactams (aztreonam) used for?
What is special about monobactams ?
You can give them to people with beta lactamase allergies (except for specific allergies to ceftazidime
What is your glycopeptide drug?
What is your short acting glycopeptidase?
Who should you avoid giving telavancin for?
What is vancomycin used to treat?
What are Adverse effects of Vancomycin?
Red man syndrome, nephrotoxocity, ototoxicity
What should you monitor vancomycin for?
What are your long acting lipoglycopeptides?
What does oritavancin inhibit?
Warfarin -> may cause bleeding
What are long acting lipoglycopeptides(oritavancin, dalbavancin) good for?
What is so special about long acting lipoglycopeptides?
They have long half life (>7 days); 1 dose= 2weeks of therapy
What are your cyclic lipopeptides?
What is daptomycin used for?
MRSA and VRE (vancomycin resistant)
Daptomycin cannot be used to treat for?
Pneumonia(rendered inactive by surfactant)
What must you monitor for daptomycin?
Creating kinase (CK) concentrations
Adverse effect of daptomycin (cyclic lipopeptides)
What are your Oxazolidinones?
What are linezolid/tedizolids used for?
What are adverse effects of oxazolidinones?
Thrombocytopenia due to bone marrow suppresion
What syndrome do oxazolidinones cause with SSRIs?
What are your tetracyclines?
What are your glycylcyclines?
What are class tetracyclines good for?
Atypicals, community acquired MRSA
What are adverse effects of tetracycline, doxycycline, and minocycline?
Photosensitivity, discoloration of developing teeth, bone growth retardation
What is tigecycline good for?
Adverse effect of glycocylcycline?
Photosensitivity; discoloration of developing teeth; bone growth retardation
What are some DDIs for tetracyclines group and glycocylcyclines?
DDI with multivitamins, calcium, iron, antacids
Which cycline has a very high Vd (low blood concentration?
What are tetracyclines group Contraindiciated for?
Pregnant; children less than 8
What is the lincosamides?
What is it good for?
Gram + aneorobes; strap (including MRSA)
Adverse effects of clindamycin?
Diarrhea-> potential to cause C-diff
What drug causes potential for C-diff ?
What are streptogramins drugs?
What are quinupristin/dalfopristin good for?
Enterococcus faecium (including VRE)
What are your macrolides?
Euthyro, clarithro, and azithromycin
What is your ketolides?
What are adverse effects of macrolides and ketolides?
QTC prolongation -> use with caution
What are your aminoglycosides
To army in
What are common side effects of gentamicin, tobramycin, amikacin, and streptomycin
What are your fluoroquinolones?
What does levofloxacin cover?
What fluoroquinolone covers strep pneumonia?
Levofloxacin and moxifloxacin
Side effects of fluoroquinolones?
QT prolongation; C diff colitis, tendonitis, tendon rupture, myasthenia Travis, photosensitivity,
What are CI's of fluoroquinolones?
Pregnant women and kids
What's the BBW for fluoroquinolones?
PO forms of fluoroquinolones should be avoided with?
Cheating agents ( calcium, magnesium, aluminum, etc)
Which conditions are fluoroquinolones reserved for?
Sinusitis, bronchitis, cystitis for patients with no alternative tx options
What are your folate antagonist drugs?
Bactrim = Trimethoprim (TMP)/ Sulfamethoxazole (SMX)
What does it treat for?
Community acquired MRSA
What are adverse effects of folate antagonist?
Rash; SJS syndrome; hyperkalemia;
What is the gold standard drug for treating aneorbic activity (both gram + and -)
What is your nitroimidazole drug?
What are adverse effects of metronidazole?
Metallic taste, dry mouth, disulfiram-line reaction with consumption of alcohol
What should you not take with metronidazole
What are your lower UTI drugs?
What does fosfomycin treat for?
NTF and fosfomycin are ineffective for infections outside of ?
Lower UTI (cystitis)
Polymyxin B and colistin covers?
Multi drug resistant A. Baumannii, p.aeruginosa, and k. Pneumoniae
Adverse reactions of polymyxins and colistin?
What is first line for C.diff?
What is used for recurrent C-diff?
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