Home
Subjects
Textbook solutions
Create
Study sets, textbooks, questions
Log in
Sign up
Upgrade to remove ads
Only $35.99/year
Acute phase reactants
STUDY
Flashcards
Learn
Write
Spell
Test
PLAY
Match
Gravity
Terms in this set (11)
What is ESR?
Erythrocyte sedimentation rate
Old, well-established acute phase reactant
Measures the distance that erythrocytes have fallen after one hour in a vertical column of anticoagulated blood (measured in mm/hr)
Primarily affected by fibrinogen
What is CRP?
C-reactive protein
Acute phase protein synthesized by the liver
Part of the innate immune system
5 positive acute phase reactants (apart from CRP and ESR)
Ferritin
Procalcitonin (specific for infection)
Fibrinogen
Alpha-1 antitrypsin
Haptoglobin
3 negative acute phase reactants
Albumin
Transferrin
Transthyretin
What are the advantages of ESR?
Better established
Cheaper (therefore more widely available)
What are the advantages of CRP?
More sensitive
More specific
More responsive to changes in inflammatory state
What are 2 conditions that elevate ESR in the absence of an inflammatory state?
Anaemia
Macrocytosis
What are 2 conditions that depress ESR?
Polycythaemia rubra vera
Leukocytosis
What are the 4 conditions that must be considered in a patient with an extremely elevated ESR (>100)?
Infection
Malignancy (particularly multiple myeloma)
Renal conditions (end-stage renal failure, nephrotic syndrome)
Inflammatory disorders (particularly temporal arteritis/polymyalgia rheumatica)
What is the most common cause of elevated CRP?
Infection
Which conditions is ESR useful in the diagnosis of?
Temporal arteritis
Polymyalgia rheumatica
Sets with similar terms
Ch 25 - Burns - Acute Phase
62 terms
Drug Cards Units 21, 22, 15, 16, 17, 23, 24, 25
43 terms
Acute and Chronic Renal Disease
58 terms
Acute Kidney Injury
60 terms
Sets found in the same folder
Delirium
6 terms
Hyperkalemia
11 terms
Tremor
8 terms
Heart failure aetiologies
7 terms
Other sets by this creator
Primary Billiary Cholangitis
9 terms
Parkinson's disease
9 terms
Medication management in AKI
5 terms
Syphilis
10 terms
Other Quizlet sets
4540 Inner Ear Disorders
59 terms
Regents Review Packet
17 terms
APART STUDY QUESTIONS
95 terms
Related questions
QUESTION
what is the generic for Vemlidy?
QUESTION
what is the only treatment for fulminate hepatic failure?
QUESTION
What is the most common cause of OBSTRUCTIVE pancreatitis?
QUESTION
What are some consequences of portal HTN?