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Pediatric Dosage Rules and Calculations
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Terms in this set (13)
Young's Rule for Child's Dosing
age in years/ (age in years + 12) x adult dose= child dose
Drilling's Rule
adult dose x (age in yrs./20) = child dose
Fried's Rule
adult dose x (age in months/150)
-better to use in infants until 2 years old and the age of the child is expressed in months
Clark's Rule
adult dose x (weight in lbs./150)
-based on weight in pounds
Average adult's BSA
1.85 meters squared
(body weight of 70kg and a height of 175 cm)
Child's dose relative to BSA
adult dose x (child's BSA/average adult's BSA (1.85 meters squared))
Mostellar equation for BSA
square root of (height in cm x weight in kg)/3600
steps to solve a dilution problem w/ the proportional technique
1. set up the proportion equation
2. solve for x, which is the total # of units of active ingredient in the solution
3. calculate the amount of diluted solution that should be made using proportions
4. calculate x to obtain the total amount of diluted solution that can be made
5. to find out how much diluent to add, subtract the original amount of solution from the total amount of diluted solution
V/V ratio
-volume/volume ratio
-unit: mL
-1:500= 1mL/500 mL = 0.2%
W/W ratio
-weight/weight ratio
-unit: g
-5:100= 5g/100g= 5%
W/V ratio
-weight/volume ratio
-unit: g/mL
-10/100= 10g/100mL= 10%
How much sterile water should be used to dilute 1L of 70% alcohol solution to 40% solution? How much of the 40% solution is made in total?
70%/1000mL=40%/X
X=1000mL x 40%/70%= 571.4 mL
1000mL - 571.4 mL = 428.6 mL of sterile water is added to 571.4 mL of the 70% solution to make a total of 1L
alligation method
1. Put higher concentration % on top left and lower percentage on bottom left
2. Put desired concentration (%) in middle
3. Subtract both percentages by desired and place calculated parts in X formation
4. Add each part per concentration together to get total parts
5. Divide weight or volume given by total parts to get
grams or mL PER part
6.
Multiply each part by g/part or mL/part to get amount for each concentration needed to make desired product
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