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Kine 408 CH 7-8 (2)

Terms in this set (26)

Step-By-Step Summary fo the Sliding Filament Theory (Excitation-Contraction-Coupling-Relaxation):

-Steps 1-3 are _____ of SM.
1. A nerve signal arrives at the ______.
2. The synaptic vessels release _____ that diffuses across the _____ and binds to receptors on the _____ of the muscle fiber. This opens up _______ on the sarcolemma and results in movement of ______.
3. The inward movement of Na+ ions ________ and sends a wave through the _____.

- Steps 4-8 are ______ of SM.
4. Depolarization of the T-tubules result in the release of _______ from SR into the cytosol / _______ of SM fiber.
5. Calcium binds to _______ (on actin). Ca+ binding to troponin C results in a shift in the _______ so that ______ on actin are exposed.
6-8. These steps illustrate ________ - ______ are the S1 units pulling the actin closer together, which happens over and over again - and development of _______. Briefly, an energized myosin cross-bridge binds to the active site on actin and ________. These steps occur repeatedly as long as neural stimulation to the muscle continues.

- Steps 9-10 are _____ of SM.
9. The 1st step in muscle relaxation occurs when the motor neuron _____. Indeed , when the neural stimulation of the SM ceases, ________ is no longer released and MF is _______.
10. When the motor neuron causes to fire and muscle excitation ceases, _____ is pumped from cytosol/sarcoplasm back into the SR for ______ (back to where it came from). Without free Ca+ in the cytosol/sarcoplasm, troponin moves tropomyosin ________. This tropomyosin coverage of the active sites prevents ______ and therefore muscle relaxation occurs.