2 Written questions
2 Multiple choice questions
- Prevents cross-linking of peptides and synthesis of peptide strnd through autolysin activators. Does not allow enzyme to cross link peptide strands.
Methicillin, Oxacillin, Nafcillin, Cloxacillin, Dicloxacillin
- Ampicillin and Amoxicillin
o Broad-spectrum penicillin's; safe for prescription but not resistant to beta-lactamase
o Effective aginst gram (-)
Extended-spectrum penicillin's *not know
o Works against most bacteria, gram(-) and gram (+)
Carbenicillin, Ticaracillin, Azlocillin, Piperacillin.
- May have hypersensitive reaction (rashes, fever) that may lead to anaphylactic shock in some cases
- Can cause antiplatelet effects
2 True/False questions
Cycloserine → Competitively inhibits D-alanine ligase enzyme so cannot syntheses from L to D-alanine
Don't have crosslinking if not have D-alanine at the end
Bacitracin → Interferes with dephosphorylation of isoprenyl pyrophosphate; molecule carries peptidoglycan building blocks