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"most common" & case study 24: Breast Patho
Q5 GNMD 6024 Quiz 5 (Lasku)
Terms in this set (17)
What is the most common
of the breast (and young females)?
What is the most common
that leads to the development of acute mastitis?
What is the most common cause (most important etiological factor) of fat necrosis?
What is the most common disorder (and
) of the breast?
Why is fat necrosis important?
The calcified mass can mimic a breast carcinoma on mammography
What percentage of environmental factors lead to breast cancer?
of those environmental factors, 30% of women develop spontaneous carcinoma of the breast (HER2/neu)
how does obesity play an important role in breast carcinoma?
Fat tissue contains androgens that are converted to estrogen. Prolonged exposure to estrogen prediposes the breast
Where is the cancer of the breast most commonly developed?
Upper outer quadrant of the left breast
What is the most common cancer (carcinoma) of the breast?
Invasive ductal carcinoma at 70-80%
where does breast cancer most commonly mastasize to?
axillary lymph nodes
Where do most breast cancer spread to from the axillary lymph nodes?
Lungs & bones
what is the the approximate percentage of women with some irregular texture/density in the breast(s) on palpation/mammography?
What are favorable prognosis?
1. DNA ploidy status
2. "S-phase" fraction value
3. estrogen & progesterone receptor pos
bad prognosis: metastasis to axillary lymph nodes, HER2/neu gene, neg ER & PR
Among women with fibrotic changes in the breast, the greatest risk of developing a breast cancer is seen among patients with:
A. Apocrine metaplasia
C. Cystic change
D. Sclerosing adenosis
E. Atypical ductal hyperplasia
atypical ductal hyperplasia
The most important prognostic factor for patients with the disease is the status of:
A. DNA ploidy
B. ER Estrogen receptor
E. Axillary lymph node
axillary lymph node
A predisposition to carcinoma of the breast is associated with which of the follow?
A. The number of first degree relatives with the same disease
B. History of the same disease in other breast
C. The age at which the first child is born
E. All of the above
All of the above
Which of the following genetic anomalies is considered likely to be useful in identifying women at risk for this patient's disease?A. Amplification of EGFR oncogene
B. Mutation of the p53 gene
C. Mutation of the Rb gene
D. Inheritance of mutated BRCA-1 gene
E. Strong staining for cathepsin D
Inheritance of mutated BRCA-1 gene
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