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5 Written questions

5 Matching questions

  1. hepatitis B
  2. cirrhosis
  3. cirrhosis pathology
  4. hepatitis A
  5. varices from portal HTN
  1. a esophageal, hemorrhoids, umbilical
  2. b transmission: FECAL-ORAL
    hep A antigen
    anti-HAV antibody
    NO chronicity
    30 days incubation
  3. c transmission: sexual, parental/body fluids, vertical (placental)
    HBsAg, HBcAg, HBeAg
    anti-HBs, anti-HBc, anti-HBe
    5-10% chronicity
    60 days incubation
  4. d IR inflammatory dz => disruption of liver structure and fxn
    diffuse fibrosis and nodular regen => cobblestone appearance
  5. e liver inflammation/necrosis =>
    fibrosis
    dec bilirubin metabolism
    pain/fever/N/V,fatigue
    dec estrogen/androgen metabolism
    dec CHO, protein, fat metabolism

5 Multiple choice questions

  1. ALT/SGPT is most sensitive
    AST/SGOT
    LDH
    alkaline phosphatase
    GGT
  2. obesity, middle age, female, familial
  3. => biliverdin => unconjugated bilirubin (insoluble/indirect) => bound to albumin for transport to liver => CONJUGATED with glucuronic acid (water soluble/direct) => ileum/colon (bacteria) => urobilinogen => bowel (brown feces) => plasma => kidney (yellow urine)
  4. EtOH
    biliary blockage
    hyperlipidemia
    smoking
    stones
  5. portal HTN => dec liver metab => inc ammonia/toxin => blood and BBB => GIB byproducts => irritability, convulsions, coma

5 True/False questions

  1. hepatitis Ctransmission: parental/body fluids, sexual, vertical
    s/s: absent but LFT positive for HCV
    HC antigen and anti-HCV antibody
    90% chronicity
    20% => cirrhosis

          

  2. hepatitis pathologyinflam of liver => varying severity of hepatic cell damage => kupffer cell hyperplasia => infiltration of phagocytes to necrosis and scarring => alters microvasculature => portal HTN => liver failure and death

          

  3. bilirubin metabolism=> biliverdin => unconjugated bilirubin (insoluble/indirect) => bound to albumin for transport to liver => CONJUGATED with glucuronic acid (water soluble/direct) => ileum/colon (bacteria) => urobilinogen => bowel (brown feces) => plasma => kidney (yellow urine)

          

  4. phases of hepatitis: prodromalresolution of jaundice
    dec s/s but hepatomegaly and liver tenderness
    2-12 wks for normalization

          

  5. obstructive jaundice: extrahepaticstone/tumor CBD
    inc conjugated (direct) bilirubin