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Pharmacology Chapt: 35, 36, 37, 38
Terms in this set (44)
Work to maintain homeostasis
Glucagon and insulin
Diagnosed in the second or third trimester of pregnancy.
Test is done by drinking nasty liquid
Gestational diabetes mellitus GDM
Check for a fasting blood sugar
Glucose tolerance test GTT
Hgb A1 C
Testing for diabetes
Known as a mini A1 C test checks blood level over the previous one or three weeks
What range is considered Hyperglycemia
Greater than 100
What is known for cause of ketosis and acidosis it must be treated properly?
This association recommends patient with pre-diabetes be treated to prevent or delay on set of type two diabetes.
Patient must also exercise at least 150 minutes per week or five days 30 minutes in a week
American diabetes Association
What status is important when assessing a diabetic patient?
Psychosocial or mental status
Sufficient reason to investigate for nutrition related causes
Change in body weight of more than 10 pounds or 10% of body weight in less than six months
Consist of patient glucose level record
Each hospital may have their own perimeter
Glucose sliding scale
This is the only insulin that can be given intravenously
What is the best site for insulin injection
Pancreas secretes insulin at steady rate of what?
30 to 50 units daily
Average rate of insulin secretion in adult
Two insulins that should NEVER be mixed?
Glargine & detemir
Rotation of injection site is important to avoid atrophy or hypertrophy.
This slows the absorption rate for insulin
Albuterol, calcitonin, clozapine, olanzapine, corticosteroids, diltiazem, Diuretics
Anabolic steroids, aCE inhibitors, Alcohol, nonselective beta adrenergic blocking agents, calcium, fluoxetine, ethanol, lithium, insulin, MAOI's
Large birth of infants
Biguanide Oral antidiabetic agents.
First drug of choice
Causes weight loss and lowers triglycerides
No value for type 1
Sulfonylurea Oral Hypoglycemic agents
Three factors Important insulin therapy
Onset, peak, and duration
Nonsulfonylurea or hypoglycemic agents
Skip a meal skip a pill
Meglitinide Oral Hypoglycemic agents
Thiazolidinedione Oral Antidiabetic agents
Combination of sulfnylureas or metfromin to lower blood glucose level.
Does not cause hypoglycemia by itself.
Alpha-Glucosidase inhibitor agents
Symlin Pen, pramlintide
Sodium-Glucose Cotransporter 2 Inhibitors
Mimics action of incretin
Incretin Mimetic Agents
Glucagon-like peptide-1 Agonist(GLP-1)
Dipetidyl Peptidase-4 Inhibitors
Secreted by Alpha cells or the pancreas
Breaks down store glycogen to glucose, resulting elevated blood glucose levels
Signs and symptoms are polydipsia, polyuria, polyphagia, weight loss and fatigue.
Type one diabetes
Lethargic, weight gain, increased appetite, weak, fatigue, and subnormal body temp
Bounding pulse(even during sleep),
Cardiac enlargement, palpation, dysrhythmias
Agent that works by blocking synthesis of T3 and T4 in the thyroid gland.
Congenital hypothyroidism occurs when a child is born without a thyroid gland or one that is hypoactive.
Disorder of salt and water metabolism mark by polyuria and polydipsia
Transports glucose through the cell to be used for energy, Signals deliver to take up glucose and stored as glycogen
Action of insulin
What labs need to be checked when checking for kidney dysfunction?
BUN and creatinine
Lispro U-100 (Humalog)
Lispro U-200 (Humalog 200)
Onset of Action: 15-20 min
(Clear) Rapid Acting
Regular U-100 (Novolin R, Humulin R)
Humulin R Regular U-500
Onset of Action: 30-60 min
(Clear) Short Acting
NPH (Novolin N, Humulin N, ReliOn)
Onset of Action: 2-4 hrs
Glargine U-100 (Lantus) 1-2 hr
Glargine U-100 (Basaglar) 1-2 hr
Glargine U-300 (Toujeo) 6 hrs
Detemir (Levemir) 1-2 hr
Degludec U-100 & U-200 (Tresiba) 1-4hrs
(Cloudy) Long Acting
Insulin should be mixed in what order?
Clear to cloudy
THIS SET IS OFTEN IN FOLDERS WITH...
Pharmacology intro ch. 1-11
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