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NAPLEX random things to know

Terms in this set (75)

*learning IV meds chapter has its own quizlet
refer to that quizlet
what is MOA of ranolazine?
unique feature?
inhibits Na current - does not decrease HR or BP
Increases QT interval
3A4 substrate
MOA of clopidogrel?
irreversibly inhibits ADP receptor - P2Y12 subunit on platelets
what HR to titrate in stable angina while on BB?
55-60 bpm
what drugs worsen HF?
DI NATION
D- DPP4 inhibitors - sitagliptin, alogliptin
I - immunosupp - TNF alpha inhib, interferons
N - non DHP CCB
A - antiarrythmics - class 1 (dipyridamole, quinidine, profafenone, lidocaine, mexilitine, flecainanide, procainamide)
T - TZDs (pioglitazone - fluid retention)
I - itraconazole
O - oncology
N - Nsaids, steroids
furosemide IV stored how?
room temp
max dose of bisoprolol? metoprolol XL? carvedilol?
for HF
bisoprolol 10 mg/day
metop XL 200 mg/day (can be cut in half)
carvedilol 25 mg BID <85 kg, 50 mg BID >85 kg
metoprolol IV to PO ratio
1:2.5
do not start aldosterone receptor antagonists in HF when?
if K>5 or GFR<30 or Scr >2.5 (males) or >2 (females)
who is BiDil indicated in HF? starting dose and target dose?
for AA in Class III-IV still symp despite tx or cannot tolerate ACEI/ARB
decreases mortality!

titrate 1 tab BID to 2 Tabs TID
digoxin therapeutic range in HF? Afib?
0.5-0.9 ng/ml - HF
0.8-2 ng/ml - afib
what electrolytes increase risk for dig toxicity? DDI cyp?
DECREASE K, Mg
INCREASE Ca
3a4 substrate
ivabridine (Corlanor) MOA?
when to use?
SE?
inhib f current in SA node - decrease HR (dec hospitalizations but not mortality)

use when EF <35 and HR >70 (target HR 50-60)
use when on max BB dose or CI to BB

causes phosphenes - bright flashes of light
how to admin microK, Klorcon-M, Klor-con, K-tab?
microK- open cap, sprinkle on food
Klorcon-M - tab cut in half or dissolve in 4oz water
Klocon - swallow whole
K-tab-swallow whole
MOA of entresto?
blocks neprilysin and AT1 receptor, hence the actions of angiotensin II
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