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50 terms

test 4 (skin and eye infections)

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staph skin diseases
VIRULENCE FACTORS
coagulase
proteases, lipases, hyaluronidase
penicillinase
exfoliative toxin
staphylokinase
staph virulence factor
COAGULASE
impedes progress of leukocytosis into infected areas by produceing clots
staph virulence factor
PROTEASES, LIPASES, HYALURONIDASE
degrade surrounding tissues so the infection can spread
staph virulence factor
PENICILLINASE
degrade penicillin
staph virulence factor
EXFOLIATIVE TOXIN
causes seperation of the dermis and epidermis
staph virulence factor
STAPHYLOKINASE
digests blood clots
FOLLICULITIS
disease caused by staph aureus
inflammation of the hair follicle
HIDRADENITIS
dz caused by staph aureus
inflammation of a gland
FURNUCLES (BOILS)
dz caused by staph aureus
when the infection extends from the follicle or gland into surrounding tissues
CARBUNCLES
dz caused by staph aureus
larger, deeper leisions resulting from inter connection of multiple furnucles
IMPETIGO
dz caused by staph aureus
superficial skin infection that causes the skin to flake or peel off
CELLULITIS
dz caused by staph aureus
caused by fast-spreading infection in the dermis and subcutaneous tissues
SCALDED SKIN SYNDROME (SSS)
dz caused by staph aureus
system infection mediated by phage-encoded exfoliative toxins in the blood stream
NECROTIZING FASCIITIS "FLESH-EATING" DISEASE
dz caused by staph aureus
enzymes adn toxins destroy tissue causing movement of the bacteria into deeper tissues
STREP SKIN DISEASE
VIRULENCE FACTORS
streptokinase
hyaluronidase
M protein
Streptolysins SLO and SLS
strep virulence factor
STREPTOKINASE
cleaves plasminogen to degrade tissues
strep virulence factor
HYALURONIDASE
digests hyaluronic acid
strep virulence factor
M PROTEIN
inhibits phagocytosis
strep virulence factor
STREPTOLYSINS SLO AND SLS
hemasins
IMPETIGO
dz caused by strep pyogenes
CELLULITIS
dz caused by strep pyogenes
NECROTIZING FASCIITIS
dz caused by strep pyogenes
ERYSIPELAS
dz caused by strep pyogenes
GAS GANGRENE
-caused by Clostridium perfingens
-gases produced from fermentation of amino acids and glycogen in the dead tissues
-tx debridement, sx, hyperbaric oxygen therapy, amputation
CHICKEN POX
-vesicular rash dz
-caused by varicella zoster virus
-shingles- can occur years after exposure and is caused by latent virus in CNS
-attenuated vaccine is available
CONGENITAL VARICELLA SYNDROME
when mothers contract varicella zoster virus early in pregnancy
SMALL POX
-vesicular rash dz
-caused by variola virus
-prevented with vaccinia vaccine (cow pox)
MEASLES (rubeola)
-maculopapular rash dz
-caused by measles virus
-characterized by appearance of sm. oral leisions known as Kopliks spots
-prevented with attenuated MMR vaccine
--complication of =
Subacute sclerosing panencephalitis (SSPE)- slow progressive brain degeneration 2-10yrs after infection
RUBELLA (german measles)
-maculopapular rash dz
-caused by rubella virus
-2 forms
*postnatal- acquired after birth
*congenital rubella syndrome- virus obtained in utero
-prevented with attenuated MMR vaccine
ERYTHEMA INFECTIOSUM (fifth disease)
-maculopapular rash dz
-caused by parvo virus B19
-rash resembles slapped cheek and then spreads to other parts of the body
EXANTHEM SUBITUM (roseola)
-maculopapular rash dz
-caused by human herpes virus type 6 (HHV-6)
-begins abruptly with high fever that may cause convulsions
WARTS (papillomas)
-wartlike eruptions
-caused by human papilloma virus (HPV)
-benign, squamous epithelial growth on skin or mucous membranes
EXAMPLES
-common warts
-plantar warts
-flat warts
MOLLUSCUM CONTAGIOSUM
-wartlike eruptions
-caused by a pox virus
-leisions are smooth, waxy nodules containing a milky virus filled fluid
LEISHMANIASIS
-large pustular skin leison
-caused by the protozoan Leishmania
-zoonotic dz tranmitted by sand flies
3 TYPES:
-cutaneous leishmaniasis
-mucocutaneous leishmaniasis
-systemic leishmaniasis
DERMATOPHYTES
most common cause of fungal skin infections
--causative agents include: trichophyton, microsporum, epidermonphyton
TINEA CAPITUS
fungal infection of scalp
TINEA CORPIS
fungal infection of body
TINEA BARBAE
fungal infection beard
TINEA MANUUM
fungal infection of hand
TINEA CHURIS
fungal infection of groin aka jock itch
TINEA AXILLARIS
fungal infection of arm pit
TINEA PEDIS
fungal infection of feet aka atheletes foot
TINEA LINGUIUM
fungal infection of nares
TINEA VERSICOLOR
fungal infectoin with patchy scaling
BACTERIAL CONJUNCTIVITIS
commonly cause by staph epi, strep sp, haemopilus, influenzae, moraxella sp.
NEONATAL EYE INFECTIONS
commonly caused by Neisseria gonorrhea and Clamydia trachomatis
VIRAL CONJUNCTIVITIS
commonly caused by adenovirus
TRACHOMA
chronic infection of the epithelial cells of the eye caused by Clamydia trachomatis
-pannus- infiltration of leukocytes causes a pseudomembrane of inflammatory cells to form over the cornea
KERATITIS
invation of deep eye tissues that can lead to complete corneal destruction
-common cause is herpes simplex virus
RIVER BLINDNESS
chronic heliminth infection caused by onchecerca velvulus carrying bacteria Wolbachia
-transmitted by biting black flies