Cell Biology Quiz 5

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______ is the protein that enables DNA Pol alpha to be exchanged for DNA Pol delta.

A. RPA
B. PCNA
C. Topoisomerase
D. Beta clamp
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Terms in this set (20)
______ is the protein that enables DNA Pol alpha to be exchanged for DNA Pol delta.

A. RPA
B. PCNA
C. Topoisomerase
D. Beta clamp
B
_______ is the protein that recognizes an abasic site.

A. Uracil glycosylase
B. CSB
C. APE
D. XPE
C
______ is the enzyme that synthesizes the majority of the leading strand during S phase.

A. DNA Pol alpha
B. DNA Pol III
C. DNA Pol epsilon
D. DNA Pol beta
C
_________ is a DNA repair protein that directly reverses alkylation damage.

A. MSH2/MSH6 dimer
B. Alkylglycosylase
C. MGMT
D. BER
C
______ is a protein in a repair detection complex with Rad50 and NBS1.

A. Ku 70
B. MSH3
C. MRE-11
D. MGMT
C
_______ is a topical drug that halts DNA synthesis and that can be used to treat basal cell carcinoma.

A. MRE-11
B. Temozolamide
C. 5-Fluoro Uracil
D. Tamoxifen
C
_____ is the protein that allows strand invasion in dsDNA break repair.

A. MRE-11
B. NBS-1
C. Ku70/80
D. RAD51
D
_______ is the protein complex that recognizes large IDLs.

A. PMS2/MHL1
B. MSH2/MSH3
C. MRE11/RAD50/NBS1
D. MSH2/MSH6
B
_________ is the repair protein that prokaryotes use to correct damage caused by uv radiation.

A. MutS alpha
B. Photolyase
C. DNA Pol I (back-up)
D. Thymine glycosylase
B
_____ is the protein enzyme that can extend the telomeres.

A. TERC
B. TERT
C. DNA Pol beta
D. PCNA
B
______ is formed when methyl-cytosine is deaminated. A. Uracil B. 6MethylA C. Thymine D. 8oxoGC_______ is a repair pathway that uses microhomology to repair DNA breaks. A. NER B. MMR C. NHEJ D. HRC_____ is a structure that forms after homologous chromosomes join in dsDNA break repair. A. Alkylation end joining B. Coil-coils C. Holliday Junctions D. Thymine dimersC_______ is the process of vascularizing tissue. A. Angiogenesis B. Initiation C. Promotion D. DifferentiationA______ is the DNA repair pathway that would target PAHs. A. NER B. MMR C. BER D. HRA______ is the detachment and spread of primary cancer cells. A. Loss of Heterogeneity B. Differentiation C. Metastasis D. AnaplasiaC______ is the condition where a cell has two copies of a mutant allele. A. Loss of Heterozygosity B. Hypomethylation C. Loss of Heterogeneity D. HyperchromaticA_____ is the characteristic behavior of a cell that has lost DNA repair ability. A. Hypomethylation B. Hyperplasia C. Differentiation D. Mutator PhenotypeD_______ is the bacterial protein that cleaves the DNA strand containing a mispaired nucleotide. A. MUTL B. MUTS C. PMS2 D. MUTHD______ is the term that describes incorrect chromosome separation during M phase. A. Nondisjunction B. Loss of Heterozygosity C. Anaplasia D. Cancer PromotionA