Animal ___ are chemical signals that are secreted into the circulatory system and communicate regulatory messages within the body. For an example, they control insect metamorphosis.
Two systems coordinate communication throughout the body: the ___ system and the ___ system.
The ____ system secretes hormones that coordinate slower but longer-acting responses including reproduction, development, energy metabolism, growth, and behavior.
The ____ system conveys high-speed electrical signals along specialized cells called ___; these signals regulate other cells.
Chemical signals bind to receptor proteins on ____. Only these can respond to the signal.
Hormones, local regulators, neurotransmitters, neurohormones, and pheromones are types of what?
_____ (hormones) are secreted into extracellular fluids and travel via the bloodstream.
growth, development, reproduction
Hormones mediate responses to environmental stimuli and regulate ___, ___, and ___.
In contrast to endocrine glands, ____ have ducts and secrete substances onto body surfaces or into body cavities; e.g. tear ducts.
____ are chemical signals that travel over short distances by diffusion. They help maintain blood pressure, nervous system function, and reproduction.
Local regulators are divided into two types: ___ signals act on cells near the secreting cell, and ___ signals act on the secreting cell itself.
Neurons (nerve cells) contact target cells at ___. At these, neurons often secrete chemical signals called ____ that diffuse a short distance to bind to receptors on the target cell.
___ are a class of hormones that originate from neurons in the brain and diffuse through the bloodstream.
____ are chemical signals that are released from the body and used to communicate with other individuals in the species. They mark trails to food sources, warn of predators, and attract potential mates.
polypeptides, amines, steroids
Three major classes of molecules function as hormones in vertebrates: ____, ____, and ____.
The two water soluble molecules that function as hormones are ____ (a polypeptide) and ____ (an amine).
The two lipid soluble molecules that function as hormones are ____ (a steroid) and ____ (an amine).
The binding of a ___-soluble hormone to a receptor on a cell leads directly to gene regulation in the nucleus, which eventually leads to a cytoplasmic response. These hormones can easily pass through membranes.
The binding of a ___-soluble hormone to a receptor on a cell lead either to gene regulation in the nucleus or to a cytoplasmic response. These hormones cannot easily pass through membranes.
The solubility of a hormone correlates with the location of ____ inside or on the surface of target cells.
____ in frogs promotes resorption of the tadpole's tail in addition to regulating metabolism.
receptors, pathways, proteins
The same hormone may have different effects on target cells that have different ___ for the hormone, different signal transduction ____, or different ____ for carrying out the response.
The hypothalamus, pineal gland, pituitary gland, thyroid gland, parathyroid glands, adrenal glands, kidneys, pancreas, and ovaries are all examples of major ____.
A ___ loop inhibits a response by reducing the initial stimulus. It regulates many hormonal pathways involved in homeostasis.
islets of Langerhans
The pancreas has clusters of endocrine cells called ____ with alpha cells that produce glucagon and beta cells that produce insulin.
uptake, breakdown, fat
Insulin reduces blood glucose levels by promoting the cellular ___ of glucose, slowing glycogen ____ in the liver, and promoting ___ storage.
Glucagon increases blood glucose levels by
Stimulating conversion of glycogen to glucose in the liver and stimulating breakdown of ___ and ___ into glucose.
___ is the best-known endocrine disorder. It is caused by a deficiency of insulin or a decreased response to insulin in target tissues. It is marked by elevated blood glucose levels.
Type ___ diabetes mellitus (insulin-dependent) is an autoimmune disorder in which the immune system destroys pancreatic beta cells.
Type ___ diabetes mellitus (non-insulin-dependent) involves insulin deficiency or reduced response of target cells due to change in insulin receptors.
In insects, molting and development are controlled by a combination of hormones: A brain hormone stimulates release of ___, a molting hormone, from the prothoracic glands.
In insects, molting and development are controlled by a combination of hormones: ____ promotes retention of larval characteristics.
The ____receives information from the nervous system and initiates responses through the endocrine system.
Attached to the hypothalamus is the ____, which is composed of the posterior pituitary and anterior pituitary.
A hormone can stimulate the release of a series of other hormones, the last of which activates a nonendocrine target cell; this is called a ____ pathway. These are regulated by negative feedback.
The release of ___ hormone results from a hormone cascade pathway involving the hypothalamus, anterior pituitary, and thyroid gland.
A ____ regulates the function of endocrine cells or glands. The four strictly tropic hormones are: Thyroid-stimulating hormone (TSH), Follicle-stimulating hormone (FSH), Luteinizing hormone (LH), and Adrenocorticotropic hormone (ACTH).
A ____ targets nonendocrine tissues. Nontropic hormones produced by the anterior pituitary are: Prolactin (PRL) and Melanocyte-stimulating hormone (MSH).
parathyroid hormone, calcitonin
Two antagonistic hormones regulate the homeostasis of calcium (Ca2+) in the blood of mammals: ____ (PTH) is released by the parathyroid glands and ____ is released by the thyroid gland.