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Pharm II Exam 1

Terms in this set (28)

catapres (clonidine)/methyldopa
alpha 2 agonist
catapres (clonidine)
dont let so much norepi into synaptic cleft. results in vasodilation.
Tx: HTN
catapres (clonidine)
be careful with sudden withdrawal (can cause rebound HTN)
catapres (clonidine)
S/E: drowsiness/sedation
beta 2 agonists
albuterol, metaproterenol, terbutaline
beta 2 agonists (albuterol, metaproterenol, terbutaline)
causes smooth muscle relaxation in bronchioles --> bronchodilation
beta 2 agonists (albuterol, metaproterenol, terbutaline)
tx: asthma, emphysema, bronchitis, and hypersensitivity, anxiety
beta 2 agonists (albuterol, metaproterenol, terbutaline)
S/E: jittery, increased HR, hypokalemia
alpha 1 blockers
drugs that end in "osin"
methyldopa
alpha 2 agonist that treats HTN in moms
dangerous combo b/c they do the same thing so it can become toxic
if pt is on cholinergic and cholinesterase inhibitors what can that do
alpha 1 agonist
neosynephrine
Neosynephrine
alpha one agonist that treats the common cold (OTC)
pt's with HTN
who do you need to be cautious when giving neosynesphrine
sedation/drowsiness
side effects of alpha 2 agonists
alpha 1 blockers (osin)
blocks the alpha receptors --> vasodilation and decreased BP
side effects of alpha 1 blockers (osin)
sexual dysfxn, syncope, increased drowsiness, ortho HypoTN, need to recumbent 3-4 hours
beta-blockers (lol)
decreases HR and BP
asthma and COPD (non-selective and will bronchoconstrict)
what do you need to be cautious of when giving beta blockers?
bradycardia, cardiogenic shock, heart block
contraindicated for beta-blockers
asthma, renal disorders, COPD, concurrent use w/ diuretics, digoxin, DM
use with EXTREME CAUTION with beta-blockers
calcium channel blockers
relaxes coronary artery spasms and peripheral arterioles
calcium channel blockers
decreases afterload, peripheral resistance, workload
calcium channel blockers, statins, ARBS
dont drink grapefruit with these medications
Nifedipine, Verapamil, Diltiazem
calcium channel blocker examples
ACE inhibitors
indicated for HTN and HF
ACE inhibitors
work by decreasing peripheral resistance and decrease blood volume (BLOCKS vasoconstriction, BLOCKS water retention)
Side effects of ACE inhibitors
persistant cough, hyperkalemia, angioedema
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