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PDA 1 Exam 1
Terms in this set (11)
After learning physiology of female reproduction, do you think therapeutic interventions at what stages could be targeted for effective contraception?
prevent ovulation of mature oocyte, change motility of fallopian tube, slow sperm movement through cervix, changes uterine tissue
Based on aromatase inhibitors mechanism of action, which disease state would it be useful in?
endometriosis, hormone-responsive breast cancer, performance enhancing in athletes
What are the potential adverse effects of aromatase inhibitors? And what is a supplemental strategy used in such situations?
can lead to loss of bone density, can employ add back therapy and calcium supplement
The mid cycle LH surge that triggers ovulation is the direct result of hypothalamic positive feedback by which hormone?
estradiol (main source of estrogen in the body)
True or false: thecal cells make steroid precursors essential for the synthesis of estrogen
how does progesterone concentrations change throughout pregnancy
steadily increases till birth than drops off
How is the change in progesterone in pregnancy different than that during menstrual cycle?
hCG secretes progesterone, these secretions taper off around 10-12 weeks of pregnancy
What happens if effects of progesterone changes are blocked during pregnancy?
pregnancy may be terminated
What are the side effects of a hysterectomy?
symptoms of menopause
What hormonal treatment is helpful following a hysterectomy?
estrogen and progestin
Can GnRH antagonists or long-acting GnRH agonist be used for contraception? What are their limitations?
Yes, but not good in practice because of risk of osteoporosis and hypogonadism
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