A&P lecture 9 part 3 main points

Briefly describe the events involved in initiating muscle contraction (starting at the motor neuron up to the release of Ca from the SR)
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(1)Nerve impulse reaches axon terminal → voltage-gated calcium channels open → ACh released to synaptic cleft
(2)ACh binds to its receptors on sarcolemma → opens ligand-gated Na+ and K+ channels → end plate potential → Opens voltage-gated Na+ channels → AP and AP propagation across the sarcolemma down into the t-tubules
(3)Voltage-sensitive proteins in T tubules (DHP receptors) change shape in response to AP and activate the Ryanodine receptors→ SR releases Ca2+ to cytosol