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EXAM VII: FOLIC ACID DEFICIENCY

FOLIC ACID DEFICIENCY
STUDY
PLAY
FAD
TREATMENT:
Goal is to treat the underlying cause of the anemia, which may be due to diet or a malabsorption disease.

Oral or intravenous folic acid supplements may be taken on a short-term basis until the anemia has been corrected, or -- in the case of poor absorption by the intestine -- replacement therapy may be lifelong.

Dietary treatment consists of increasing the intake of green, leafy vegetables and citrus fruits
FAD
TESTS:
(CBC) shows anemia and large red blood cells.
A bone marrow examination is rarely necessary, but shows megaloblasts
serum folate levels
FAD
SYMPTOMS:
Tiredness
Headache
Sore mouth and tongue (stomatitis)
Pallor (skin paleness)
Cheilosis (scales and fissures of the mouth)
Dysphagia
FAD
CAUSES:
Poor diet: can be obtained by leafy greens, liver
Some medications, such as Dilantin (phenytoin), methotrexate interfere with the absorption .
Alcohol abuse
Malabsorption syndromes
Hemodialysis
FAD
Decrease in red blood cells (anemia) caused by _________

Red cells are abnormally large and are called megalocytes, or megaloblasts in the bone marrow.

Subsequently, this anemia may be referred to as megaloblastic anemia