Exam 3 Substance Use disorders

Differentiate between dependence, tolerance, and addiction
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Terms in this set (19)
Differentiate between dependence, tolerance, and addiction
Dependence- Repeated use with or without physical dependence (addiction, withdrawal)
Tolerance- After repeated use, the drug has a lesser effect so you need a higher dose to achieve same effect
Addiction- Deprivation gives rise to symptoms and urge to get more
Use the DSM 5 criteria for substance use disorders to recognize a patient struggling with addiction given a clinical scenario
These are all common sense. Tolerance, withdrawal, increased use, cravings.
Need 2/11 to diagnose

Only 2 that do not count are pt w opiod and develop tolerance and withdrawal but they are following their prescription orders
Describe the psychological consequences of alcohol dependency
You feel terrible
Depression, suicidality, anxiety, mood and behavior changes

alcohol blocks SSRI effects
Identify the primary location of alcohol metabolism in the body
Liver does 90%
Identify the nutritonal deficiency that leads to Wernicke encephalopathy and Korsakoff syndrome
Thiamine Deficiency
Recognize the symptoms of mild alcohol withdrawal given a clinical scenario
Anxiety, nausea, headache, insomnia, tachycardia, increase BP
Differentiate between alcoholic hallucinosis and delirium tremens
Hallucinosis- You have visual hallucinations (you see insects or animals in your room), starts 12 hours after last drink and lasts 48 hours

Delirium Tremens-Hallucinations and DELIRIUM, aggitation, autonomic instability (increased HR, BP, sweating). Starts 76-96 hours after last drink.
Identify the 3 most common screening methods for alcohol use disorder
CAGE
Audit-C
Asking "how many times in the past year have you had 5 (men), 4 women, drinks in a day
Identify the 3 FDA approved meds for alcohol use disorder
Disulfiram
Acamprosate
Naltrexone
Identify the health consequences of opioid use disorder
High comorbidity with psych illness

infection, death, overdose, amnesia
Recognize the signs and symptoms of opioid withdrawalAgitation, fidgety, sweating, vomiting, diarrhea, urinatingCompare the 3 FDA approved medication assisted treatments available for opiate use disorder in terms of MOAMethadone- Full agonist Buprenorphine- Partial agonist Naltrexone- AntagonistIdentify the life saving intervention for opioid overdoseNaloxone (Narcan)Recognize the symptoms of cocaine intoxicationHeart issues! Energetic, alertness, sociability, insomnia, strokeIdentify the type of treatment modality for cocain use disorder with proven efficacyPsychosial intervention! Clincal based therapyRecognize the physiologic effects of nicotine useMost addictive substance after 1st use Increased HR, BP, concentration, dopamine releaseDiscuss the available pharmacologic interventions for smoking cessationNRT- Gum, patch, lozenge Varenicline (chantix)- partial agonist for DA release Buproprion- DA reuptake inhibitor, makes cigs taste badIdentify the psychoactive component of cannabisTHCIdentify the potential risk associated with cannabis useAnxiety, psychosis, mood disorders, Cannaboid Hyperemesis Syndrome