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Maryville Pharm Exam 4 BEST REVIEW YOU WILL FIND
This is Dr. Jessica Blands test review. THIS IS THE BEST ONE!
Terms in this set (13)
What is the Mechanism of action of an inhaled muscarinic receptor antagonist? Also known as anticholinergic or LAMA or SAMA
Examples: Spiriva and Atrovent
an inhaled muscarinic receptor antagonist suppresses the M3 receptor response (Airway smooth muscle) and prevents the activation by acetylcholine.
Used to treat COPD and Asthma
Spiriva is better absorbed in the lungs (LAMA)
Atrovent is short acting and used for bronchospasms (SAMA) , slower than a B2.
What is Fluticasone (Flovent) used to treat?
inhaled: maintenance drug for asthma and off label used for COPD
What is the normal dosage of Fluticasone (Flovent)?
100mcg BID as maintenance. *Daily without regard to symptoms
What is important teaching for patients taking Fluticasone (Flovent)
If taking a bronchodilator administer this between 5-15 minutes before taking Flovent
Avoid smoking, smoke filled rooms, people with URI, and other triggers.
Report S/S of Cushing Syndrome
THIS IS A MAINTENANCE DRUG. NOT used for acute attacks
Rinse mouth after every use to prevent infections (Thrush)
What is the MOA for benzonatate (Tesselon Pearles)
Benzonatate is an antitussive that anesthetizes the stretch receptors in the lungs.
What is the MOA for inhaled corticosteriods such as QVAR, Pulmicort, Flovent, Asmanex?
These drugs inhibit IgE and mast cell migration of inflammatory cells into bronchial tissue.
They prevent the transcription of genes that contribute to inflammation.
What is the MOA of Nasal corticosteriods such as Nasonex or Flonase?
They interrupt inflammation by inhibiting the synthesis of inflammation mediators
What is Loperamide use to treat?
Chronic diarrhea r/t IBD
Acute nonspecific diarrhea in patients over the age of 2
reduce ileostomy volume
OTC: travelers diarrhea
What is the MOA of Loperamide?
Loperamide is an antidiarrheal. It works by stimulating the MU opioid receptors to decrease intestinal motility.
Decreases peristalsis, prolongs transit times, reduces fecal volume, increases viscosity, decreased fluid and electrolyte loss, Antisecretory, increased sphincter tone.
What is the MOA for Omeprazole?
Omeprazole is used to treat GERD, esophagitis, PUD
it is a pro-drug that irreversibly combines with the H+ K+ ATPase proton pump system. It reduces blood flow to the stomach, decreases pepsin secretion, and increases serum pepsinogen.
OR/AND. . .
Acid reducer/PPI that suppresses gastric basal and stimulated acid secretion by inhibiting the parietal cells H+K+ ATPase pump.
*reduces blood flow tot he stomach. decreases pepsin. increases serum pepsinogen.
What is the MOA of histamine 2 receptor antagonists?
Zantac, Pepcid, Tagamet
Inhibits the action of histamine at H2 receptors. Suppresses both basal and meal stimulated acid production and reduces the total pepsin output.
What is the first line of treatment for an URI in a child under the age of 6?
Supportive care. Avoid OTC other than tylenol for a fever reducer.
hydration, warm liquids, saline nasal spray, humidified air.
What are antihistamine (H1 antagonist) side effects?
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