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Terms in this set (6)
e.g. H5N1: avian influenza virus
Enters the host cell, and the RNA is translated to DNA by reverse transcriptase. The viral DNA copy is then integrated into the host chromosome where it exist latently.
Human immunodeficiency virus. When infected cells (CD4+ T cells) become activated, they release free virus by budding or cell-cell fusion. Lysis of the CD4+ cells also releases HIV into the blood, resulting in reduced CD4+ count and suppression of immune response.
Traits of a microbe that promote pathogenicity.
- Toxins: alter/destroy normal function of host or host cells. Exotoxins, endotoxins.
- Adhesion factors
- Evasive factors: evading the host's immune system
- Invasive factors: facilitate penetration of anatomic barriers and host tissue.
Subset of cytokines. Responsible for direction the migration of leukocytes to areas of injury and to areas where the immune response has been activated (spleen, tonsils, Peter Patches)
pro- or anti-inflammatory proteins secreted by cells in innate and adaptive immune system.
Interleukins, interferons (IFNs), tumor necrosis factor alpha (TNF-alpha)
ILs: enhance the acquired immune response or regulate inflammatory process.
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