Reproductive diseases (not all)

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Benign prostatic hyperplasia

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Terms in this set (18)

Benign prostatic hyperplasia

Prostate gland enlarged but not cancerous

What growth stages goes the prostate through?

1. in the early puberty - doubles in size
2. age 25 - continues during remainder of life.

Complications of benign prostatic hyperplasia

Impingement on urethra --> obstruction of urine flow --> bladder wall thickening --> bladder weaken and loose ability to empty completely.

benign prostatic hyperplasia: etiology

Risks:
>40 years
Family history
Type 2 Diabetes
Lack of physical activity

May be a result of decreasing testosterone and increasing estrogen in the blood.
DHT is the same with age. People that do not produce DHT do not get BPH.
Does NOT developed in males where the testicles were removed before puberty.

benign prostatic hyperplasia: pathogenesis and clinical manifestations

Static component: Increase in prostatic size --> weak urinary straem, postvoid dribbling, frequent urination, nocturia,

Dynamic component: Prostatic smooth muscle tone

Third component: Detrusor (muscle) instability and impaired bladder contractility.

Urinary retention, urinary incontinece, urinary urgency (inability to delay urination and trouble starting the stream), pain after ejaculation or during urination, urine with an unusual color or smell.

May not know that they have BPH until they cannot urinate.

Antihistamines can weaken the force of contraction of bladder muscles, cause retention etc.
Size of prostata don't necessarily correlate with the degree of symptoms.