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Immunology week1 chapter1
Terms in this set (30)
What is immunology?
The study molecules, cells, organs, and systems responsible for the recognition and disposal foreign material ; the study of the reaction of a host when foreign substance is introduced into the body.
What is immunity?
The condition of being resistant to an infection.
The study of non-cellular components of blood.
What are antigens/immunogens?
Foreign substances that induce an immune response.
What are lymphokines?
Soluble cytokines that are antigen stimulated secreted from lymphocytes to affect the function of activity of cells/tissues.
What is the function of the immune system?
To recognize self from non self and to defend the body against non self. To detect and eliminate mutated cells to maintain homeostasis.
What are the immune systems defense mechanisms?
Inflammation, Phagocytosis, Antibody synthesis and memory, Effector T-lymphocytes, Complement, Removal of dying cells.
What is adaptive immunity?
Acquired immunity when the body encounters and responds to a specific antigen.
What is innate immunity?
Nonspecific natural immunity one is born with that is the first line of defense and has no memory to defend the body of foreign antigens.
What are the characteristics of the immune system?
Specificity, mobility, memory, replicability, cooperatively
What is humoral immunity?
The primary defense against extracellular organisms. The response that is mediated by the B-lymphocytes (B-cells) where antibodies are produced by B-lymphocytes and plasma cells.
What is the cell-mediated immunity?
The primary defense against intracellular organisms. It is the response that is mediated by T-lymphocytes or Cytotoxic T-cells. The link between phagocytic cells and T-lymphocytes.
What immunity is apart of the Adaptive immunity?
Humoral and Cell-mediated immunity.
What are the phases of the immune response ?
Recognition phase and Response phase
In which phase of the immune Response does the body recognize foreign proteins, amino acids, carbohydrates, enzymes, toxins, discriminate self from non-self, and has a complex interaction between chemical messengers and cells of the immune system?
The Recognition phase
What happens in the Response phase of the immune response?
Elimination of foreign particles.
What are the 3 R's in the adaptive immunity characteristics?
Recognize , Respond, Remember.
What factors are involved in the Innate immunity?
Physical and chemical barriers (skin, mucous membranes), Secretions,( tears, sweat, saliva, mucus) inflammation, Cellular components (macrophages/phagocytosis and neutrophils) ,Plasma proteins (complement and acute phase proteins.)
What is Active immunity?
When the host is exposed to the foreign antigen, the host immune cells respond by producing specific antibodies. Occurs when exposed to stimulating agent or immunization. Lifetime lasting.
What is passive immunity?
The transfer of pre-formed antibody to the host that are short term and no memory cells are produces.
Which process works by training the immune system to recognize and combat pathogens?
What word is latin for cow?
What is the actual use of organisms that has been treated to prevent infection?
Who discovered the relationship between the exposure cowpox to immunity to smallpox?
What did Louis Pasteur do?
Applied the principle of attenuation to a rabies vaccine,
What is the function of the helper T cell (CD4)?
Assist by activation of B-lymphocytes.
Which cell is responsible for killing cells that are affected by tumor cells or a virus?
Cytotoxic T-cells (CD8)
Which organ's main function is to filter lymph fluid?
What is the function of the spleen?
To filter old cells, damaged cells, and foreign antigens form the blood.
What are the sites of hematopoiesis?
Bone marrow, proximal end of bones, sternum (adults) Spleen and liver (children)
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