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Band Neutrophil (clumped chromatin)

Agglutination (suggests Ab attachment to RBC such as in IMHA)

Anaplasma marginale (bovine anaplasmosis caused by intraerythrocytic rickettsia - most prominent tick borne disease in cattle - can cause fatal hemolytic anemia)

Babesia canis (causes hemolytic anemia and thrombocytopenia)

Basophilic Stippling (abnormal retention of ribosomes - sometimes caused by intense regenerative anemias or lead poisoning - normal in ruminants)

Torocytes (formed by drag/force of blood flow through small vessels)

Cytauxzoon felis (tick transmitted protozoan that infects RBC associated with Theileria - disease is usually fatal - Clinical Signs: lethary, anorexia, fever, icterus, hemolytic anemia - often non-regenerative)

Distemper Viral Inclusions (Traditional wright stain)

Eccentrocytes (shifting of HgB to one side - caused by oxidative injury like ingestion of Onions in dogs - commonly seen w/Heinz body formation)

Echinocytes (numerous short spicules - in-vivo can be caused by electrolyte imbalances, kidney disease, or rattlesnake envenomation)

Acanthocyte (unevenly distributed projections, due to changes in lipid concentration in RBC membranes - Cats w/ Hepatic Lipidosis OR dogs w/ Hemangiosarcoma)

Equine Eosinophil

Ghost RBC (complement has lysed this RBC infected with mycoplasma haemofelis causing it to lose its HgB)

Heinz Bodies (Oxidative denatured HgB)

Hemobartonella canis (usually causes disease in splenectomized or immunosuppressed patients - Clinical Signs: anemia, icterus)

Howell Jolly Bodies (nucleus remains - indication of immature RBC release - Seen w/regenerative anemias, non-functioning spleens, or splenectomies, and increased corticosteroids)

Hypochromatic Erytrhocyte (decreased HgB from Fe deficiency

Keratocyte ("Helmet Cells" - 2 spicules present - can be present in Fe+ deficiency)

Leptocytes ("Target Cells")

Reactive Lymphocyte

Metamyelocyte (Bean-shaped)


Monocyte (basophilic cytoplasm, open chromatin nucleus, vacuoles)

Mycoplasma haemofelis (presence of the organism on RBC will cause IMHA - can cause severe hemolytic anemia- transmitted by flea/ticks - Clinical Signs: anemia, splenomegaly, fever, lethargy, icterus)

Mycoplasma wenyoni (bacteria found in RBC)

Nucleated RBC (

Schistocytes (Erythrocyte fragments caused by DIC, vascular tumors, or Fe+ deficiency anemia)

Red Cell Leukemia (erythremic myelosis)

Polychromatic Reticulocytes (wright stain - cause by a result of regeneration following blood loss or blood destruction - sign of recovering bone marrow)

Rouleaux Formation (normal in horses - suggests increase globulin in small animals)

Spherocytes (smaller, lack central pallor - indicator of IMHA - complement eats membrane and destroys the disc shape)

Polychromatic Reticulocytes (stained with methylene blue - indicates regenerative anemia - such as blood loss or blood destruction)

Stomatocytes (mouth like area in the middle of RBC - hereditary in Alaskan malamutes, Minature schnauzers)

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