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Pathology Wk. 3 + 4

Terms in this set (79)

Two classes of molecules associated with microbes or injured/necrotic host cells are recognized by pattern...: ...and...
Two classes of molecules associated with microbes or injured/necrotic host cells are recognized by pattern recognition receptors (PRRs): Pathogen-associated molecular patterns (PAMPs) and Damage-associated molecular patterns (DAMPs).
When one of the PRRs recognize a PAMP or DAMP, the host cells release...mediators that elicit an...
When one of the PRRs recognize a PAMP or DAMP, the host cells release inflammatory mediators that elicit an inflammatory response.
An example of a PRR is ...-... receptors, which recognize products of bacteria and viruses. Another example of a PRR is an inflammasome, which recognizes...
An example of a PRR is Toll-like receptors, which recognize products of bacteria and viruses. Another example of a PRR is an inflammasome, which recognizes products of dead cells.
The two major participants in the inflammatory reaction are...
The two major participants in the inflammatory reaction are blood vessels and leukocytes.
SIRS (systemic inflammatory response syndrome) refers to...An example of SIRS is..., which occurs as the result of a disseminated...
SIRS (systemic inflammatory response syndrome) refers to a local inflammatory response becoming systemic. An example of SIRS is sepsis, which occurs as the result of a disseminated bacterial infection.
The 5 cardinal manifestations of inflammation are...
The 5 cardinal manifestations of inflammation are redness (rubor), heat (calor), swelling (tumor), pain (dolor), and loss of function.
...and...are two cardinal manifestations of inflammation both mainly caused by dilation of small blood vessels and increased blood flow.
Redness (rubor) and heat (calor) are two cardinal manifestations of inflammation both mainly caused by dilation of small blood vessels and increased blood flow.
Protein-rich fluid that flows into extravascular tissue at the sight of inflammation is called inflammatory edema or...
Protein-rich fluid that flows into extravascular tissue at the sight of inflammation is called inflammatory edema or exudate.
Fluid loss at the sight of inflammation leads to increased concentrations of RBCs, increasing viscosity and slowing blood flow, leading to a condition called...
Fluid loss at the sight of inflammation leads to increased concentrations of RBCs, increasing viscosity and slowing blood flow, leading to a condition called stasis.
With stasis, leukocytes are displaced to the periphery of vessels in a process called..., which sets the stage for leukocyte emigration through the vessel wall.
With stasis, leukocytes are displaced to the periphery of vessels in a process called margination, which sets the stage for leukocyte emigration through the vessel wall.
...are typical of non-inflammatory conditions, while...are typical of inflammatory conditions.
Exudates are typical of non-inflammatory conditions, while transudates are typical of inflammatory conditions.
The definition of edema is excess...can be either...
The definition of edema is excess fluid in the interstitial tissue or serous cavities. Can be either exudate or transudate.
Transudate is defined as...with low..., little to no..., and low...
Transudate is defined as extravascular fluid with low protein content (mostly albumin), little to no cellular contents, and low specific gravity.
Exudate is defines as...with..., cellular..., and high...
Exudate is defines as extravascular fluid with high protein content, cellular debris, and high specific gravity.
Pus or purulent exudate is defined as exudate rich in...
Pus or purulent exudate is defined as exudate rich in leukocytes (mainly neutrophils, dead cellular debris, and dead microbes).
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